Results 51 to 60 of about 110,623 (268)

The Morphometrics of “Masculinity” in Human Faces

PLOS ONE, 2015
In studies of social inference and human mate preference, a wide but inconsistent array of tools for computing facial masculinity has been devised. Several of these approaches implicitly assumed that the individual expression of sexually dimorphic shape features, which we refer to as maleness, resembles facial shape features perceived as masculine.
Mitteroecker, Philipp, Windhager, Sonja, Müller, Gerd B., Schaefer, Katrin   +3 more
openaire   +6 more sources

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Does The Use of A Combination of Spirulina and Indigofera Affect The Morphometric Development and Body Weight of Muscovy– Local Ducks (Jumbo Ducks) during The Starter Phase? [PDF]

BIO Web of Conferences
This study aimed to investigate the effects of the combination of spirulina and Indigofera in feed on the morphometric development and body weight of Muscovy–local duck crossbred (Jumbo duck) (Cairina moschata) during the starter phase.
Tistiana Heli, Widodo Eko, Adli Danung Nur   +2 more
doaj   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Prevalence of Eimeria spp. in calves from dairy farms in northern Paraná state, Brazil

Revista Brasileira de Parasitologia Veterinária, 2018
Bovine coccidiosis is a disease of major importance in cattle herds across the world. The disorder mainly affects young calves, and E. bovis and E. zuernii are considered the most pathogenic species of the genus, however, E.
Sérgio Tosi Cardim, Mércia Seixas, Victor Bittencourt Dutra Tabacow, Alessandra Taroda, Priscilla Gomes Carneiro, Thais Agostinho Martins, Luiz Daniel de Barros, Ana Flávia Minutti, Andreas Lazaros Chryssafidis, Odilon Vidotto, João Luis Garcia   +10 more
doaj   +1 more source

Easternmost Locality Record and Morphological Data of Cyrtopodion scabrum (Heyden, 1827) (Squamata: Gekkonidae) in southeastern Anatolia, Turkey

Turkish Journal of Bioscience and Collections, 2020
The locality record of the Rough Bent-toed Gecko (Cyrtopodion scabrum) from the Silopi District of the Şırnak Province of Turkey was provided in the present study.
Halime Koç, Ufuk Bülbül, Zeynep Aslan
doaj   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Análise multivariada das medidas morfométricas de potros da raça Mangalarga Marchador: análise discriminante Multivariate analysis of body measures in Mangalarga Marchador foals: discriminant analysis

Revista Brasileira de Zootecnia, 2005
Objetivou-se, com este trabalho, avaliar as medidas morfométricas de potros e potras da raça Mangalarga Marchador utilizando a análise discriminante. As medidas corporais foram feitas na semana do nascimento dos potros, em 55 potros e 41 potras; aos seis
Luís Fernando Batista Pinto, Fernando Queiroz de Almeida, Celia Raquel Quirino, Grasiele Coelho Cabral, Pedro Cezar Nehme de Azevedo, Edson Mauro Santos   +5 more
doaj   +1 more source