Results 101 to 110 of about 74,164 (284)

Senile Octodon degus Reproductive Strategy: Morphometric and Histological Description of the Penis

open access: yesInternational Journal of Medical and Surgical Sciences, 2018
This paper deals with the efficiency of in vivo gene transfer to the mouse cauda epididymis and its relation to androgens. Previous experiments in the female reproductive tract have indicated that the efficiency of transfection is related to the hormonal stage of the animal, nevertheless no analysis have been done in the male tract.
María Reyes   +2 more
openaire   +2 more sources

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen   +8 more
wiley   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

First Report of Albinism in the Threatened Gillbacker Sea Catfish Sciades parkeri (Siluriformes, Ariidae)

open access: yesBrazilian Archives of Biology and Technology, 2017
A sexually mature albino specimen of the Gillbacker Sea Catfish species Sciades parkeri (Siluriformes, Ariidae), a vulnerable species, was captured in northern Amazon estuary, State of Pará, Brazil.
Marcelo C. Andrade   +3 more
doaj   +1 more source

Morphological diversity of Meloidogyne spp. from carrot (Daucus carota subsp. Sativus) in Vietnam [PDF]

open access: yes, 2019
Carrot (Daucus carota subsp. Sativus) is known as one of the most widely cultivated and widely consumed vegetables in the world due to its nutritional and economic values.
Le, Thi Mai Linh   +4 more
core  

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

open access: yesAdvanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang   +7 more
wiley   +1 more source

Comparison of different statistical approaches to evaluate morphometric sperm subpopulations in men

open access: yesAsian Journal of Andrology, 2016
This study was designed to characterize morphometric sperm subpopulations in normozoospermic men by using different statistical methods and examining their suitability to classify correctly different sperm nuclear morphologies present in human ejaculates.
Jesús L Yániz   +7 more
doaj   +1 more source

Morphological descriptions and morphometric discriminant function analysis reveal an additional four groups of Scylla spp

open access: yesPeerJ, 2020
There are four species of mud crabs within the genus Scylla, and most of them live sympatrically in the equatorial region. Apart from a report in Japan about the finding of a natural Scylla hybrid more than a decade ago after the division of genus Scylla into four species by Keenan, Davie & Mann (1998), no subsequent sighting was found.
Fazhan, Hanafiah   +9 more
openaire   +4 more sources

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Description and molecular phylogeny of a new and one known needle nematode of the genus Paralongidorus (Nematoda: Longidoridae) from grapevine in Portugal [PDF]

open access: yes, 2018
A new and a known longidorid nematode, Paralongidorus lusitanicus n. sp. and Paralongidorus plesioepimikis, are described and illustrated from populations extracted from soil associated with grapevine (Vitis vinifera L.) from Escaroupim and Pó (central ...
Castillo, P   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy