Results 51 to 60 of about 20,071 (258)

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

On the occurrence of the rare Long-nosed Stargazer Ichthyscopus lebeck (Bloch & Schneider, 1801) (Uranoscopidae) in the coastal waters off Visakhapatnam, India

Journal of Threatened Taxa, 2018
Ichthyscopus lebeck (Bloch & Schneider, 1801) is recorded for the first time from Visakhapatnam coastal waters, Andhra Pradesh, India.  The specimens were collected from Visakhapatnam fisheries harbour.
Govinda Rao Velamala, Muddula Krishna Naranji   +1 more
doaj   +1 more source

First record of the invasive Nile Tilapia, Oreochromis niloticus (Linnaeus, 1758) (Perciformes, Cichlidae), on Bawean Island, Indonesia [PDF]

Check List, 2019
In 2018 we captured specimens of Oreachromis niloticus (Linnaeus, 1758) from Danau Kastoba, a crater lake on Bawean (Indonesia), a small, isolated island in the Java Sea. Additional individuals were later photographed.
Veryl Hasan, Muhammad Badrut Tamam
doaj   +3 more sources

A descriptive and morphometric study of the fabellofibular, arcuate popliteal and popliteofibular ligaments

Anatomy, 2015
Objectives:  The anatomical relationship of the fibrous structures in the posterolateral corner of the knee is highly complex, with many different descriptions of these structures in the literature. Discrepancy in the definitions of FF, AL and PF are a problem for both clinicians and anatomists. This study aimed to examine these structures and describe
Kurtoğlu, Zeliha, ELVAN, Özlem, AKTEKİN, Mustafa, ÇOLAK, Mehmet   +3 more
openaire   +3 more sources

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Integrative Descriptions of Two New Tardigrade Species along with the New Record of Mesobiotus skorackii Kaczmarek et al., 2018 from Canada

Diversity, 2021
Two new tardigrade species from a moss sample collected in Canada, one representing Macrobiotus hufelandi complex and the second one belonging to the genus Bryodelphax, are described.
Pushpalata Kayastha, Milena Roszkowska, Monika Mioduchowska, Magdalena Gawlak, Łukasz Kaczmarek   +4 more
doaj   +1 more source

Morphometric description of the subfascial intermuscular adipose tissue of anterior compartment of the leg

Anatomy, 2023
Objectives: To describe the morphological characteristics of subfascial intermuscular adipose tissue (IMATS) in the anterior compartment of the leg, considering its developmental and functional relationship with the crural fascia. Methods: In twenty formalin-fixed cadaveric legs (13 males, 7 females), after removal of the skin and crural fascia, the ...
İnci Kesilmiş, Zeliha Kurtoğlu Olgunus   +1 more
openaire   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Vocalizations, morphological variation, and morphometry of Pristimantis gutturalis (Anura: Strabomantidae)

Phyllomedusa: Journal of Herpetology, 2022
Pristimantis gutturalis is a species of the P. conspicillatus group described from French Guiana, with distribution so far restricted to the eastern Guiana Shield. Some aspects of this species are yet understudied, including its vocal repertoire
André Gomes Lopes, Fillipe Pedroso-Santos, Jackson Cleiton Sousa, Joandro Pandilha Santos, Carlos Eduardo Costa-Campos   +4 more
doaj  

On catch of deep-sea shark Chlamydoselachus anguineus (Chlamydose¬lachidae) on Emperor Seamounts

Известия ТИНРО, 2018
Description of frill shark Chlamydoselachus anguineus (TL 134.3 cm) is presented that was caught in the pelagic layer of the North-West Pacific in June 1979, including surface morphometric parameters and data on number of vertebras, teeth rows, and ...
V. N. Dolganov
doaj   +1 more source