Results 81 to 90 of about 1,021,613 (342)
Advanced Science, EarlyView.This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source
Effect of dietary supplementation with insect fats on growth performance, digestive efficiency and health of rabbits [PDF]
, 2019 Background: The present work aimed at evaluating the effect of the dietary replacement of soybean oil (S) by two types of insect fats extracted from black soldier fly larvae (H, Hermetia illucens L.) and yellow mealworm larvae (T, Tenebrio molitor L.) on
Biasato, I. +10 more
core +2 more sources
Advanced Science, EarlyView.A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi +11 more
wiley +1 more source
Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age [PDF]
, 2018 Cortical bone is permeated by a system of pores, occupied by the blood supply and osteocytes. With ageing, bone mass reduction and disruption of the microstructure are associated with reduced vascular supply.
A Goring +10 more
core +5 more sources
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
SLOPE PROFILE MORPHOMETRY AS AN INDICATOR FOR SLOPE MOVEMENT [PDF]
Journal of Sciences, Islamic Republic of Iran, 2001 Two dimensional slope profile morphometric investigation in a part of the land failure prone Garhwal region of the Lesser Himalaya, Tehri district, U. P., India, indicates that the landslip morphology is closely related to the dominant movement processes
doaj
Scale-dependence of lithological control on topography: Bedrock channel geometry and catchment morphometry in western Scotland [PDF]
, 2010 We propose that a scale-dependent topographic signature of erodibility arises due to fluvial and glacial erosion acting on different parts of the landscape at different times.
Bishop, P. +3 more
core +3 more sources
Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells
Advanced Science, EarlyView.This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh +11 more
wiley +1 more source
Polish Journal of Pathology, 2021 Fifty-one liver tissue biopsies of full-term stillbirths from HIV-mono-infected mothers were investigated. All morphometric indices of non-parenchymal liver cells were calculated using the Avtandilov microscopic morphometric grid, which consisted of 100 ...
Sergey Sherstiuk +3 more
doaj +1 more source
Assessing the reproducibility of discriminant function analyses. [PDF]
, 2015 Data are the foundation of empirical research, yet all too often the datasets underlying published papers are unavailable, incorrect, or poorly curated. This is a serious issue, because future researchers are then unable to validate published results or ...
Albert, Arianne YK +5 more
core +3 more sources