Results 111 to 120 of about 104,341 (285)

Gait Adaptability Training Improves Gait in Spinocerebellar Ataxia Patients

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Spinocerebellar ataxia (SCA) is a rare, genetic neurodegenerative movement disorder primarily affecting the cerebellum. So far, there is no available cure for SCA. However, evidence suggests that neurorehabilitation can alleviate symptoms.
Colette J.M. Reniers   +5 more
wiley   +1 more source

Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia

open access: yesMovement Disorders, EarlyView.
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing   +22 more
wiley   +1 more source

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

open access: yesMovement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker   +30 more
wiley   +1 more source

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

open access: yesMovement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani   +3 more
wiley   +1 more source

Morphometric and morphological analysis of the optic canal in adult human cadavers and dry skulls

open access: yesCurrent Medicine Research and Practice
Background: The optic canal, which connects the middle cranial fossa to the orbit, houses critical neurovascular structures. Its morphometric and morphological characteristics are essential for neurosurgical planning and anthropological studies.
Ashwini Bala Saheb Nuchhi   +3 more
doaj   +1 more source

Deep learning‐based H&E‐derived risk scores in colorectal cancer: associations with tumour morphology, biology, and predicted drug response

open access: yesThe Journal of Pathology, EarlyView.
Abstract Over recent years, several deep learning (DL) models have been presented to predict colorectal cancer (CRC) patient survival directly from haematoxylin and eosin (H&E)‐stained routine whole‐slide images (WSIs). Unlike traditional studies that rely on manually defined histopathological features, weakly supervised DL allows training directly on ...
Nic G Reitsam   +23 more
wiley   +1 more source

Assessing Sternal Dimensions for Sex Classification: Insights from a Greek Computed Tomography-Based Study

open access: yesDiagnostics
Background/Objectives: This study aimed to assess the potential of sternal morphometric parameters derived from multidetector computed tomography (MDCT) for sex estimation in a contemporary Greek population.
Konstantina Vatzia   +11 more
doaj   +1 more source

Spatial visualisation and quantification of expression of cell specific markers — an application for chronic parathyroiditis cases

open access: yesOpen Medicine, 2006
Kaczmarek Elżbieta   +3 more
doaj   +1 more source

Programmed unmanned aerial vehicles show great potential for monitoring marine megafauna in specific areas of interest

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Targeted conservation measures are contingent on robust knowledge of spatio‐temporal animal distribution in areas of interest. We explore unmanned aerial vehicle (UAV) transect monitoring as a novel method for standardized digital aerial surveys of marine megafauna by investigating the fine‐resolution spatio‐temporal distribution of harbour porpoises ...
Dinah Hartmann   +2 more
wiley   +1 more source

Comparative analysis of micrometric parameters in the ovaries of adolescent, elderly and senile women

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Aging is a systemic process affecting all tissues of the body. In this study, the choice of scientific interest fell on the paired gland, the key structure of the female reproductive system – the ovary.Objective: to carry out a comparative analysis of ...
A. A. Balandin   +3 more
doaj   +1 more source

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