Results 51 to 60 of about 97,304 (300)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Ten simple rules for reporting voxel-based morphometry studies [PDF]

, 2008
Voxel-based morphometry [Ashburner, J. and Friston, K.J., 2000. Voxel-based morphometry—the methods. NeuroImage 11(6 Pt 1), 805–821] is a commonly used tool for studying patterns of brain change in development or disease and neuroanatomical correlates of
Rohrer, J.D., Warren, J.D., Henley, S.M.D., Ridgway, G.R., Scahill, R.I., Fox, N.C.   +5 more
core  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Three-dimensional computer graphics-based ankle morphometry with computerized tomography for total ankle replacement design and positioning

, 2017
Morphometry of the bones of the ankle joint is important for the design of joint replacements and their surgical implantations. However, very little three-dimensional (3D) data are available and not a single study has addressed the Chinese population ...
Kuo, Chien-Chung;Lu, Hsuan-Lun;Leardini, Alberto;Lu, Tung-Wu;Kuo, Mei-Ying;Hsu, Horng-Chaung, 呂東武   +1 more
core   +1 more source

voxel‐based morphometry study [PDF]

, 2016
Multitasking refers to the ability to organize assorted tasks efficiently in a short period of time, which plays an important role in daily life. However, the structural neural correlates of multitasking performance remain unclear.
Yi Wang, Tian‐xiao Yang, Yuxiu Sui, Tian-xiao Yang, Rui-ting Zhang, Chen‐yuan Zhang, Eric F. C. Cheung, Chen-yuan Zhang,, Rui‐ting Zhang, Jingjing Yao, Raymond C. K. Chan   +10 more
core   +1 more source

Spermatozoa morphometry and ultrastructure in estuarine crocodile (Crocodylus porosus)

Asian Pacific Journal of Reproduction, 2020
Objective: To evaluate normal spermatozoa morphometry and ultrastructure in estuarine crocodile (Crocodylus porosus). Methods: Four adult male crocodiles aged between 12-15 years, with an average snout to tail length of (3.15±0.01) m were selected for ...
Wan-Nor Fitri, Haron Wahid, Putra Tengku Rinalfi, Dana Raj, Yawah Donny, Latip Qayyum, Ab Aziz Abdul Malek   +6 more
doaj   +1 more source

Clinical Validation of Artificial Intelligence (AI)‐based Cartilage Segmentation Predicting Knee Replacement

Arthritis Care &Research, Accepted Article.
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein, David J. Hunter, C. Kent Kwoh, Wolfgang Wirth   +3 more
wiley   +1 more source

Longitudinal Voxel-based morphometry with unified segmentation: evaluation on simulated Alzheimer’s disease [PDF]

, 2007
The goal of this work is to evaluate Voxel-Based Morphometry and three longitudinally-tailored methods of VBM.We use a cohort of simulated images produced by deforming original scans using a Finite Element Method, guided to emulate Alzheimer-like ...
Camara, O., Whitcher, B., Hill, D.L.G., Ridgway, G.R., Scahill, R.I., Crum, W.R., Fox, N.C.   +6 more
core  

Revisiting pancreatic islet isolation in murine models: A practical and effective technical protocol

Physiological Reports
The endocrine pancreas is composed of clusters of cell groups called pancreatic islets. These cells are responsible for the synthesis and secretion of hormones crucial for glycemic homeostasis, such as insulin and glucagon.
Aline Fernandes‐da‐Silva, Rosiane Aparecida Miranda, Patricia Cristina Lisboa, Vanessa Souza‐Mello   +3 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source