Results 101 to 110 of about 4,468,997 (324)

Stochastic mortality models: An infinite dimensional approach [PDF]

open access: yesFinance and Stochastics 18(1):209-248, 2014, 2019
Demographic projections of future mortality rates involve a high level of uncertainty and require stochastic mortality models. The current paper investigates forward mortality models driven by a (possibly infinite dimensional) Wiener process and a compensated Poisson random measure.
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Cancer incidence and mortality

open access: yesHealth at a Glance: Europe, 2019
A.G. Ramirez et al. (eds.), The South Texas Health Status Review: A Health Disparities Roadmap, DOI 10.1007/978-3-319-00233-0_5, © The Author(s) 2013 Cancer is a vital health issue in Texas.
Pamela K. Agovino, Stephanie Hill
semanticscholar   +1 more source

Mortality decrease and mathematical limit of longevity [PDF]

open access: yesarXiv, 2004
We wish to verify that the mortality deceleration (or decrease) is a consequence of the bending of the shape parameter at old ages. This investigation is based upon the Weon model (the Weibull model with an age-dependent shape parameter) for human survival and mortality curves.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Child suicide rates during the COVID-19 pandemic in England

open access: yesJournal of Affective Disorders Reports, 2021
Background: There is concern about the impact of COVID-19, and the control measures to prevent the spread, on children's mental health. The aim of this work was to identify if there had been a rise of childhood suicide during the COVID pandemic.
David Odd   +4 more
doaj  

The effect of cardiac resynchronization on morbidity and mortality in heart failure.

open access: yesNew England Journal of Medicine, 2005
BACKGROUND Cardiac resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony. We evaluated its effects on morbidity and mortality.
J. Cleland   +6 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Overweight/obesity risks and prevalence of diabetes and hypertension in North Eastern India: An analysis using seemingly unrelated probit model

open access: yesClinical Epidemiology and Global Health, 2021
Objective: It would be reasonable to hypothesize that common unobserved factors, such as psychological stress and anxiety, as well as genetic and environmental factors, simultaneously influence the tendency for overweight or obesity and the prevalence of
Strong P. Marbaniang   +3 more
doaj  

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

open access: yesNew England Journal of Medicine, 1998
BACKGROUND AND METHODS National surveillance data show recent, marked reductions in morbidity and mortality associated with the acquired immunodeficiency syndrome (AIDS).
F. Palella   +7 more
semanticscholar   +1 more source

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