Results 101 to 110 of about 13,824,619 (349)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Before the incorporation of the 13-valent pneumococcal conjugate vaccine (PCV13) into the childhood vaccination regimen in Greenland in 2010, Inuit populations experienced a substantial prevalence of invasive pneumococcal disease (IPD).
Kristiana Alexandrova Nikolova +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Global respiratory tumor mortality correlation study with economic level, 2000–2019
ObjectiveThe study aimed to investigate the relationship between global tracheobronchial lung cancer mortality rates and economic levels and assess the associated regional economic burden.
Mingjie Wang, Mingjie Wang, Zhiyuan Chen
doaj +1 more source
Trends in mortality rates from chronic forms of coronary heart disease in the regions of the Russian Federation in 2017–2021 [PDF]
I. V. Samorodskaya, I.V. Klyuchnikov
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Trends of acute myocardial infarction-related deaths in US patients from 1999 to 2020
Introduction The objective of this study was to analyze the temporal trends and demographic/geographical disparities in acute myocardial infarction (AMI)-related mortality among individuals aged 15 and older across the United Sates (US).
Irfan Ullah +14 more
doaj +1 more source
Mortality of Susceptible and Resistant Heliothis virescens Larvae Exposed to Various Petroleum Oils and Insecticide Rates [PDF]
W. P. Scott +2 more
openalex +1 more source

