Results 91 to 100 of about 42,215 (293)
Advanced Science, EarlyView.Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang +13 more
wiley +1 more source
‘Heroes aren’t always so great!’ – Heroic perceptions under mortality salience
Social Influence, 2019 According to terror management theory, in a first study (N = 80), we tested the hypothesis that heroic perceptions of historic heroes would become more positive under mortality salience.
Simon Schindler +3 more
doaj +1 more source
Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy
Advanced Science, EarlyView.Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu +6 more
wiley +1 more source
How does threat affect different types of people? Investigating a relationship between Big-Five personality and self-concept, and how threat may affect a self-concept network [PDF]
, 2020 In this exploratory project, we aim to draw connections between Big-5 personality, threat, and self-concept. In the experiment, participants first completed the Big-5 inventory of personality measuring openness, conscientiousness, extraversion ...
Connor, Kenneth
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Death Studies, 2019 This study investigates whether frequently witnessing death leads to desensitization in terms of death anxiety. A total of 163 individuals, comprising 71 doctors from branches with high death rates and 92 doctors from branches where mortality is rarely seen, participated in this study.
Gökhan Arslantürk +2 more
openaire +4 more sources
Advanced Science, EarlyView.Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang +9 more
wiley +1 more source
Conspiratorial Thinking: How Worldview and Mortality Salience Affect Belief [PDF]
, 2013 Conspiratorial thinking is widespread throughout the world, though the major social sciences have thus far chosen not to study them for a variety of reasons.
Anderson, Eric James
core
Advanced Science, EarlyView.This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen +11 more
wiley +1 more source
Decision Processes of a Suicide Bomber – Integrating Economics and Psychology [PDF]
This paper provides a theoretical analysis regarding the rationality of suicide attacks from an economist’s point of view. It is argued that although a terrorist gives up future utility from consumption by committing a suicide attack, this loss can be ...
Dirk T.G. Rübbelke, Karen Pittel
core
To Live is to Die: The Effect of Mortality Salience on Memory and Fear of Death [PDF]
, 2013 Terror Management Theory proposes that the threat of death produces existential terror, which accentuates the need for security. This effect of mortality salience awareness of death-is well documented for non-conscious thoughts of death (Martens, Burke ...
Bergamini, Tony F.
core +1 more source