Results 131 to 140 of about 37,917 (360)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Fundamental Studies of the Silicon Carbide MOS Structure

, 1999
The ability to thermally grow SiO2 on silicon carbide (SiC) has made Metal Oxide Semiconductor (MOS) devices feasible in SiC. Critical in their development is a thorough understanding of the SiC MOS structure itself.
Das, Mrinal Kanti
core  

P-GaN Tri-Gate MOS Structure for Normally-Off GaN Power Transistors

In this letter, we present a new concept for normally-off AlGaN/GaN-on-Si MOS-HEMTs based on the combination of p-GaN, tri-gate and MOS structures to achieve high threshold voltage (V-TH) and low on-resistance (R-ON).
Matioli, Elison, Erine, Catherine, Zhu, Minghua, Sohi, Pirouz, Ma, Jun, Nikoo, Mohammad Samizadeh, Nela, Luca   +6 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Effects of fundamental processing parameters on the structure and composition of two-dimensional MoS₂ films

, 2017
The unique properties resulting from strongly anisotropic chemical bonds found in the whole family of transition metal dichalcogenide materials (TMDs) have been researched for over 50 years for various applications, with MoS₂ being the most heavily ...
Waite, Adam Richard
core  

Processing Techniques of MOS Capacitors [PDF]

, 1990
Variations in both MOS capacitor structure and fabrication process were characterized using 1MHz C-V measurements. This involved processing MOS capacitors with and without backside oxide, and wet etching versus plasma ashing photoresist. The experimental
Buczkowski, Michael D
core  

Nonlinear Optical Bistability in a Bragg Reflector Multilayered Structure with MoS₂

Crystals
The special band structure of bilayer MoS2 makes it show strong nonlinear optical characteristics in the visible band, which provides a new way to develop visible nonlinear devices.
Songqing Tang, Xilei Dong, Leyong Jiang, Haishao Chen, Zhuoya Sun, Fuping Zhang, Yangbin Zhu, Yunyang Ye   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Atomic relaxation and electronic structure in twisted bilayer MoS₂ with rotation angle of 5.09 degrees [PDF]

, 2023
Somepalli Venkateswarlu, Ahmed Misssaoui, A. Honecker, Guy Trambly de Laissardière   +3 more
openalex   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source