Results 141 to 150 of about 265,712 (265)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

New insight about early miscarriage: a prenatal data-based study. [PDF]

J Transl Med
Zhu Y, Liu Y, Ren C, Liu J, Yang Q, Li N, Wang T, Zhang P, Xue J, Ren C, Liu L.   +10 more
europepmc   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Divergence in intra-tumor variant frequencies in sporadic vestibular schwannomas as a potential indication for mosaic NF2-related schwannomatosis? [PDF]

Neurogenetics
Kluwe L, Hartung T, Rosahl S, Farschtschi S.   +3 more
europepmc   +1 more source

The Mosaic of Addiction [PDF]

American Journal of Psychiatry, 2004
openaire   +2 more sources

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

CT findings in biomass smoke-associated interstitial lung disease: A retrospective analysis. [PDF]

J Clin Imaging Sci
Bendetson JG, Tran H, Kamangar MS, Fogelfeld K, Jude CM, Kamangar N.   +5 more
europepmc   +1 more source

DNA damage drives antigen diversification in Trypanosoma brucei. [PDF]

Nature
Smith JE, Wang KJ, Kennedy EM, Munday JC, Singer L, Hakim JMC, So J, Beaver AK, Magesh A, Gilligan-Steinberg SD, Zheng J, Zhang B, Moorthy DN, Brown ZE, Akin EH, Mwakibete L, McCulloch R, Mugnier MR.   +17 more
europepmc   +1 more source

Correction to “4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways”

Advanced Science, EarlyView.
wiley   +1 more source

Mosaic Inverted Hemagglutinin Extracellular Vesicle Vaccines Elicit Protective Systemic and Mucosal Immunity against Heterosubtypic Influenza Infection. [PDF]

ACS Nano
Zhu W, Wei L, Dong C, Kim JK, Bruhn M, Ma Y, Ferrante A, Arsana A, Omotara P, Kang SM, Wang BZ.   +10 more
europepmc   +1 more source