Structural insights into the mosaic and modular organization of fourteen co-occurring resistance genes in multidrug resistant Enterobacteriaceae. [PDF]
PLoS OneRossel CAJ +3 more
europepmc +1 more source
Morphological signatures of bacteria‐laden drying droplets: A multimodal analysis across host fluids
Droplet, EarlyView.Drying patterns of bacteria‐laden droplets encode concentration‐dependent signatures across three host fluids: serum, urine, and nutrient medium. By integrating time‐evolving texture descriptors, image features, and interpretable multimodal machine learning, this study demonstrates a label‐free approach for extracting information on bacterial ...
Anusuya Pal +6 more
wiley +1 more source
A Rapid and Sensitive Loop-Mediated Isothermal Amplification Assay for the Detection of Mulberry Mosaic Dwarf-Associated Virus. [PDF]
Biosensors (Basel)Sun S, Zhou X, Yang X.
europepmc +1 more source
Developmental Dynamics, EarlyView.Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm +7 more
wiley +1 more source
Enhanced recovery of terminal sequences of viral RNAs via fine-tuning of the high-throughput sequencing library preparation and evidence of a non-templated nucleotide addition at the 3' end of the minus strand in members of the genus <i>Ilarvirus</i>. [PDF]
J Gen VirolKnierim D, Margaria P.
europepmc +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Antimicrobial resistance in Neisseria gonorrhoeae isolates at the Bangrak STIs Center, Bangkok, Thailand and WGS of antimicrobial-resistant isolates, 2018-23. [PDF]
J Antimicrob ChemotherPaopang P +9 more
europepmc +1 more source
Developmental Dynamics, EarlyView.Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley +1 more source
Mosaic TLR8 gain-of-function in an elderly female treated with JAK inhibitor and adjunctive therapy. [PDF]
J Hum ImmunPatel JA +10 more
europepmc +1 more source
Developmental Dynamics, EarlyView.Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source