Results 111 to 120 of about 179,045 (295)

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

open access: yesArthritis &Rheumatology, EarlyView.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

ImprintCap, a powerful NGS-based technology to investigate the molecular background of imprinting disorders

open access: yesClinical Epigenetics
Introduction Imprinting disorders (IDs) are a rare class of diseases caused by the disruption of imprinted genes, i.e., genes with a specific pattern of expression from only one allele.
Frédéric Brioude   +6 more
doaj   +1 more source

Pest categorisation of non‐EU viruses and viroids of Cydonia Mill., Malus Mill. and Pyrus L.

open access: yesEFSA Journal, 2019
Following a request from the EU Commission, the Panel on Plant Health performed a pest categorisation of 17 viruses and viroids, herein called viruses, of Cydonia Mill., Malus Mill. and Pyrus L.
EFSA Panel on Plant Health (PLH)   +27 more
doaj   +1 more source

Development status of a Laue lens project for gamma-ray astronomy

open access: yes, 2007
We report the status of the HAXTEL project, devoted to perform a design study and the development of a Laue lens prototype. After a summary of the major results of the design study, the approach adopted to develop a Demonstration Model of a Laue lens is ...
  +21 more
core   +1 more source

Association of Clonal Hematopoiesis with Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA)
Kun Zhao   +8 more
wiley   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

open access: yesBiological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson   +9 more
wiley   +1 more source

Investigating the construction methods of an opus vermiculatum mosaic panel

open access: yes, 2010
From the third century BC to the second century AD small detailed central panels (emblemata) made using the opus vermiculatum technique were used as focal points in larger mosaic pavements. They were custom made in stone or terracotta trays to facilitate their transport and placement.
Melina Smirniou   +4 more
openaire  

A roadmap to key traits of invasive Drosophilidae

open access: yesBiological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck   +14 more
wiley   +1 more source

Gains from the upgrade of the cold neutron triple-axis spectrometer FLEXX at the BER-II reactor

open access: yes, 2013
The upgrade of the cold neutron triple-axis spectrometer FLEXX is described. We discuss the characterisation of the gains from the new primary spectrometer, including a larger guide and double focussing monochromator, and present measurements of the ...
Groitl, F.   +6 more
core   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy