The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source
Morphophysiological disorders and metabolic reprogramming in Physalis peruviana infected with the physalis rugose mosaic virus. [PDF]
Studnicka MH +11 more
europepmc +1 more source
Graft Biology in the CRISPR Era: From Tissue Fusion to Genome Compatibility
ABSTRACT Plant lineage has traditionally constrained grafting compatibility, with monocots generally considered incompatible because of their dispersed vascular bundles and limited secondary growth. Recent studies have shown that embryonic grafting can establish successful graft unions in selected monocot systems by exploiting early developmental ...
Melagani Subash Chandra Gowda Sahaja +5 more
wiley +1 more source
Integration of whey and mycorrhizal symbiosis: a sustainable biocontrol strategy against Zucchini yellow mosaic virus in squash. [PDF]
Boyno G +4 more
europepmc +1 more source
Application of Omics Technologies for Cowpea Improvement
ABSTRACT Cowpea (Vigna unguiculata) is a vital crop for food security, nutrition, and climate resilience in sub‐Saharan African and other semi‐arid regions. However, its improvement is constrained by the complexity of polygenic traits such as drought tolerance, pest resistance, and seed quality.
Junior S. Kamara +3 more
wiley +1 more source
Using Rose Bengal photosensitizer for controlling Aphis gossypii and reducing transmission of zucchini yellow mosaic virus on squash plants. [PDF]
Soliman DZ +5 more
europepmc +1 more source
Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein
Abstract Drosophila behavior/human splicing (DBHS) proteins are involved at nearly every stage of the RNA lifecycle. There are three paralogues in mammals—SFPQ, NONO and PSPC1—which form both homodimer and heterodimers. It is likely that the non‐redundant and overlapping roles of the different DBHS paralogues emerge from their dynamic and combinatorial
Andrew C. Marshall +5 more
wiley +1 more source
MutMap-Based Cloning of a Soybean Mosaic Virus Resistance Gene. [PDF]
Wang B +9 more
europepmc +1 more source
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
wiley +1 more source
The Melon Sterol Transporter Niemann-Pick C1 Protein Is a New Interactor of <i>Cucumber mosaic virus</i> Movement Protein. [PDF]
Real N +5 more
europepmc +1 more source

