THE PHYSICAL AND CHEMICAL PROPERTIES OF A DISTINCTIVE STRAIN OF TOBACCO MOSAIC VIRUS
C.A. Knight
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CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far +4 more
wiley +1 more source
Transcriptomic and metabolomic analyses reveal molecular mechanisms of tobacco mosaic virus (TMV) resistance in Nicotiana tabacum L. [PDF]
Li C +10 more
europepmc +1 more source
Electrophoresis of tobacco mosaic virus
William N. Takahashi, T. E. Rawlins
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ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve +26 more
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High Temperature Promoted the Accumulation of Citrus Yellow Mosaic Virus in Citrus sinensis via Weakening the Immune Function of the CsWRKY76-CsPR4A Modules. [PDF]
Tian XB +5 more
europepmc +1 more source
Sex as a modifier of genetic risk for type 1 diabetes
Abstract Sex differences influence the pathogenesis of type 1 diabetes (T1D), yet most genetic studies have treated sex as a control covariate rather than a dynamic effect modifier. Sex influences immune cell behaviour, including CD4+ and CD8+ T cell activation, regulatory T cell stability, B cell autoantibody production, dendritic cell priming and ...
Hui‐Qi Qu, Hakon Hakonarson
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Engineered Biomolecular Condensates Limit Tobacco Mosaic Virus Accumulation and Symptom Development. [PDF]
Stanfield AM, May JP.
europepmc +1 more source
Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
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Transcriptome Analysis of Apple Leaves with Apple Necrotic Mosaic Virus-Associated Mosaic Symptoms. [PDF]
Gao D +9 more
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