Results 101 to 110 of about 217,451 (316)
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
International Journal of Environmental Research and Public Health, 2017 Mosquito abatement programs contend with mosquito-borne diseases, insecticidal resistance, and environmental impacts to non-target organisms. However, chemical resources are limited to a few chemical classes with similar modes of action, which has led to
Jodi M. Fiorenzano, P. Koehler, R. Xue
semanticscholar +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Emerging Infectious Diseases, 2001 Fourteen isolations of West Nile (WN) virus were obtained from four mosquito species (Culex pipiens [5], Cx. restuans [4], Cx. salinarius [2], and Culiseta melanura [3]) in statewide surveillance conducted from June through October 2000.
Theodore G. Andreadis +2 more
doaj +1 more source
Parasites & Vectors, 2017 Mosquitoes are insects belonging to the order Diptera and family Culicidae. They are distributed worldwide and include approximately 3500 species, of which about 300 have medical and veterinary importance.
Diego Felipe Araujo Diniz +4 more
semanticscholar +1 more source
Oikos, EarlyView.The ecological and epidemiological consequences of species expanding into new areas are growing concomitantly with climate change. Those aiming to monitor species expanding in range must make optimal use of finite resources to deliver effective surveillance capable of detecting new incursions and range expansions.
Susanna Cant +9 more
wiley +1 more source
Tropical Medicine and Infectious Disease, 2017 Community engagement has become an increasingly important focus of global health programs. Arbovirus emergence in the Americas (Zika and chikungunya virues), and global goals for malaria and lymphatic filariasis elimination, mean that community-based ...
Kevin Louis Bardosh +7 more
doaj +1 more source
Geometric morphometrics in mosquitoes: What has been measured?
Infection, Genetics and Evolution, 2017 The field of morphometrics is developing quickly. Recent advances have enabled geometric techniques to be applied to many zoological problems, particularly those involving epidemiologically-relevant mosquitoes.
C. Lorenz +8 more
semanticscholar +1 more source
People and Nature, EarlyView.Abstract Different aspects of ecological systems, biotic or abiotic, often fluctuate in coordinated patterns over space and time. Such high concordance between ecological processes is often referred to as ecological synchrony. Human activities, including and beyond climate change, have the potential to alter ecological synchrony by disrupting or ...
Yiluan Song +9 more
wiley +1 more source