Results 161 to 170 of about 79,387 (266)

Stranger swings: Temperature-dependent upsides and downsides of a densovirus in Aedes albopictus. [PDF]

open access: yesPLoS Negl Trop Dis
Boëte C   +8 more
europepmc   +1 more source

Update on innovative surgical techniques for omphalectomy in foals

open access: yesEquine Veterinary Education, EarlyView.
Summary Umbilical infection is a common foal disorder, prone to complications, requiring surgical excision in severe cases. Timely surgical excision is the treatment of choice in these cases, as the infected umbilicus places the foal at risk for further fatal complications, such as sepsis and septic arthritis.
O. Haion   +3 more
wiley   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

open access: yesThe FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi   +8 more
wiley   +1 more source

Outcomes of dengue infection in adults with underlying haematological diseases in Brazil during 2024 and 2025

open access: yes
British Journal of Haematology, EarlyView.
K. Tozatto‐Maio   +16 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

Establishment and characterization of a Wolbachia (wAlbB)-infected Aedes aegypti line (Tw-Kao) for dengue control. [PDF]

open access: yesPLoS Negl Trop Dis
Yu HY   +15 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

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