European Journal of Dental Education, EarlyView.ABSTRACT Background Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) remain major global public health concerns. Oral lesions are often among the earliest manifestations of HIV, placing dentists at the forefront of early detection and management.
Tuğba Aydoğdu, Berkant Sezer
wiley +1 more source
Mitochondrial phylogeography and insecticide resistance of Aedes aegypti in Kenya. [PDF]
PLoS Negl Trop DisMusimbi B +7 more
europepmc +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
The FEBS Journal, EarlyView.During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Not all West Nile virus lineages behave alike: dose-response differences between lineages 1 and 2. [PDF]
Sci RepHöller P +6 more
europepmc +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Effects of different X-ray irradiation dosages on Wolbachia trans-infected and uninfected Aedes aegypti mosquitoes. [PDF]
PLoS Negl Trop DisYongyai J, Thayanukul P, Kittayapong P.
europepmc +1 more source
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
The FEBS Journal, EarlyView.C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
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Maternal and cross-stage effects of Metarhizium pingshaense fungal infection on the malaria mosquito Anopheles coluzzii life-history. [PDF]
PLoS OneSare I +9 more
europepmc +1 more source
Defining the role of αC helix interactions in the activation of the integrin αI domain
The FEBS Journal, EarlyView.The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö +7 more
wiley +1 more source
The nanosd integral gene drive enables population modification of the malaria vector Anopheles gambiae. [PDF]
G3 (Bethesda)Yen PS +11 more
europepmc +1 more source