Results 161 to 170 of about 22,950,779 (300)

All possible and most probable activity schedules in organisations

In previous studies of adaptability in buildings (Fawcett, 1979a) it has been proposed that the number of possible activity schedules for a given population may in part be used to derive a measure of adaptability.
W H Fawcett
core  

Dinâmica de rizóbios em solo do cerrado de Roraima durante o período de estiagem Dynamic of rhizobia in the soil during the dry season in cerrado of Roraima

Acta Amazonica, 2013
A fixação biológica de nitrogênio que ocorre em leguminosas é realizada por um grupo de bactérias conhecidas como rizóbios. A sobrevivência destas bactérias no solo é influenciada por diversos fatores como a temperatura, umidade e fertilidade do solo.
Jerri Édson Zilli, Gilmara Maria Duarte Pereira, Izaias França Júnior, Krisle da Silva, Mariangela Hungria, Janaina Ribeiro Costa Rouws   +5 more
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

The Most Probable Database Problem

, 2020
This paper proposes a novel inference task for probabilistic databases: the most probable database (MPD) problem. The MPD is the most probable deterministic database where a given query or constraint is true. We highlight two distinctive applications, in

core  

Kualitas Air Sumur Gali Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang Berdasarkan Indeks Most Probable Number (MPN)

Jurnal Kesehatan Andalas, 2016
AbstrakDiare merupakan salah satu penyakit yang ditularkan melalui air terkontaminasi oleh agen penyebab seperti bakteri Coliform.  Menurut data Dinas Kesehatan Kota (DKK) Padang pada tahun 2011, kejadian diare di Kelurahan Lubuk Buaya Kecamatan Koto ...
Randa Novalino, Netti Suharti, Arni Amir
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Protocol to quantify bacterial burden in time-kill assays using colony-forming units and most probable number readouts for Mycobacterium tuberculosis. [PDF]

STAR Protoc
Rabodoarivelo MS, Hoffmann E, Gaudin C, Aguilar-Ayala DA, Galizia J, Sonnenkalb L, Dal Molin M, Cioetto-Mazzabò L, Degiacomi G, Recchia D, Rybniker J, Manganelli R, Pasca MR, Ramón-García S, Lucía A, ERA4TB consortium.   +15 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source