Results 51 to 60 of about 3,162,594 (310)

Father, Womb, Blood: Apollo’s embryological theory, the ethics of revenge, and the supposed exclusion of women in Aischylos’ Eumenides

open access: yesLiteratūra (Vilnius), 2019
In Aischylos’ Eumenides, Apollo intimates a theory according to which the father is the sole genetic parent of the child. The status of this conception, and whether it is depicted as an outlandish idea, has been much and inconclusively discussed.
Johan Tralau
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A phenomenological study detailing the experiences with inclusive education in the Czech Republic for the pupil with congenital heart disease and acquired brain injury and his mother

open access: yesCogent Education
Legislative changes in the Czech Republic in 2016 created more favorable conditions for inclusive education of learners with acquired brain injury. Due to the scarcity of domestic and international evidence (only three studies) focused on this topic ...
Dagmar Sedláčková   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Effects of Urbanization on the Infant Gut Microbiota and Health Outcomes

open access: yesFrontiers in Pediatrics, 2020
Humans and their gut microbiota have co-evolved over thousands of years, resulting in the establishment of a complex host–microbiota ecosystem. Early life environmental factors, such as delivery mode, nutrition, and medication use, have been shown to ...
Siobhan Brushett   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Youthful Death and Melancholia: The Case of Rupert and Mary Brooke

open access: yesEuropean Journal of Life Writing, 2020
This article considers how Mary Brooke, the mother of the poet-soldier Rupert Brooke, managed her mourning and melancholia in the wake of the death of her sons in the First World War. It briefly considers how Brooke’s death and poetry framed and, to some
Alisa Miller
doaj   +1 more source

A Mother\u27s Work [PDF]

open access: yes, 2018
As the nursing workforce moves toward a mandate for BSN degrees, three sisters, inspired by their mother, turned to Linfield to boost their ...
Davis, Laura
core   +1 more source

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