Results 61 to 70 of about 3,162,594 (310)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Effect of maternal panic disorder on mother-child interaction and relation to child anxiety and child self-efficacy [PDF]

, 2009
To determine whether mothers with panic disorder with or without agoraphobia interacted differently with their children than normal control mothers, 86 mothers and their adolescents (aged between 13 and 23 years) were observed during a structured play ...
A Goldstein, BD McLeod, BF Chorpita, Birgit Nündel, C Faravelli, C Gerlsma, Cordelia Klein, D Silove, D Wolke, D Wolke, DH Barlow, Dieter Wolke, DR Hirshfeld, G Parker, G Parker, GS Ginsburg, HW Krohne, I Lindhout, IM Wilborg, J Bowlby, J Margraf, J Woodruff-Borden, JE Dumas, Jiske E. G. Houweling, JL Hudson, L Siqueland, LA Greco, M Jerusalem, ME Bouton, MM Weissman, N Ballash, PA Nardo Di, PM Barrett, PM DiBartolo, PS Moore, R Schwarzer, RM Rapee, S Mineka, SE Whaley, Silvia Schneider, SM Turner, Susan Gommlich-Schneider, WA Arrindell, WA Arrindell   +43 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Social Adjustment in Mothers of Children with Gender Identity

Journal of Mazandaran University of Medical Sciences, 2017
Background and purpose: Gender dysphoria is a disorder that causes problems for families and societies. This research compared the level of social adjustment between mothers of transgender children and mothers of normal children.
Mahnaz Mozaffaripour, Ezatollah kord Mirza, Mastooreh Sedaghat   +2 more
doaj  

Maternal and infant infections stimulate a rapid leukocyte response in breastmilk [PDF]

, 2013
Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and
Filgueira, L, Hartmann, P, Hassiotou, F, Hepworth, A, Lai, C, Metzger, P, Trengove, N   +6 more
core   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Le père/Méditerranée dans l'œuvre romanesque d'Emmanuel Roblès

Babel: Littératures Plurielles, 1997
Emmanuel Roblès was brought up by his mother and never met his father, who had died before he was born. Every one of his novels, particularly Saison violente, is deeply rooted in a desperate quest for the father, a painful search which joins together ...
Guy Dugas
doaj   +1 more source

www.gigisehat.id for Easy of Access to Valid Dental Health Information for Mothers of Kindergarteners

Indonesian Journal of Dental Medicine, 2020
Background: Parental attentiveness is critical during early childhood age. In consideration of the fact that child dental health problems are linked to parents’ dental health, it is necessary to not only focus on children in promoting dental health ...
Dini Parasila, Fajariana Fitriani, Thomas Reynaldi Winanto, Vita Ariesta Angesti, Fissando Yanuar Muhammad, Andry Sentosa, Lutfi Malia Rossa, Giftania Nuri Susilo, Fauzan Fauzan, Salsabila Maghfirani, Agung Sosiawan, Taufan Bramantoro   +11 more
doaj   +1 more source

The World War II Patriotic Mother [PDF]

, 2010
The archetypal good mother and the archetypal patriotic mother are important symbols in American culture. Both are rooted in maternal work but are separated by two conflicting assumptions. The good mother nurtures her children and protects them from harm,
Garner, Ana C., Slattery, Karen L.
core   +1 more source