Results 111 to 120 of about 64,662 (306)

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Management of abnormal uterine bleeding in the current realities

Репродуктивная эндокринология
Objective of the study: to optimize approaches to the treatment of abnormal uterine bleeding (AUB) in internally displaced women, considering its impact on patients’ quality of life, mental health, and daily activity. Materials and methods.
T.F. Tatarchuk, N.V. Kosei, N.F. Zakharenko, T.M. Tutchenko, O.G. Parkhometnko, T.E. Krysenko   +5 more
doaj   +1 more source

Motherhood Studies and Feminist Theory: Elisions and Intersections

, 2018
The study of motherhood has had an uneasy and ambivalent relationship to feminism and feminist theory. Ranging from radical feminist rejection of motherhood on the perceived basis of its inherent oppression of women, and the view that “motherhood has ...
Takševa, Tatjana
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Hyper-IgE Syndrome in Neonatal Period: A Clinical Challenge [PDF]

Pediatric Infectious Disease
Sharvari P Kulkarni, Tushar Parikh, Himanshi Choudhary   +2 more
doaj   +1 more source

[Neurobiology of motherhood].

Turk psikiyatri dergisi = Turkish journal of psychiatry, 2010
Motherhood is a physiological status in which certain behavioural patterns are exhibited. Maintenance of the life of the species in mammals is dependent upon the presentation of motherhood services in a certain period that the child is dependent on the mother. Absence of the mother causes some deficiencies in social, behavioural and cognitive abilities,
openaire   +2 more sources

The Long-Run Labour Market Consequences of Teenage Motherhood in Britain [PDF]

Common wisdom states that teenage childbearing reduces schooling, labour market experience and adult wages. However, the decisions to be a teenage mother, to quit school, and be less attached to the labour market might all stem from some personal or ...
Tarja K. Viitanen, Arnaud Chevalier
core  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Adverse childhood experiences, emotional distress and dissatisfaction with motherhood among first-time mothers: Mediations and child differences

Cambridge Prisms: Global Mental Health
Despite the challenges associated with motherhood, studies have not consistently identified factors contributing to first-time mothers’ dissatisfaction with motherhood in resource-limited regions.
Tosin Yinka Akintunde, Shaojun Chen, Stanley Oloji Isangha, Qi Di   +3 more
doaj   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source