Results 131 to 140 of about 89,906 (291)
Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Motherhood to Motherhoods: Ideologies of the “Feminine” [PDF]
The eleven essays in this special issue originated from the “Motherhood to mother-hoods: Ideologies of the ‘Feminine’” conference held at Chapman University in Orange, California, on April 28-30, 2023.
Lee, Nam, Osborn, Jan
core +1 more source
Economic Challenges on Motherhood and Womanhood and the Issue of Gender-Based Violence (GBV) in the South African Society [PDF]
Ovidius University Annals: Economic Sciences SeriesThis paper illustrates economic challenges on motherhood, womanhood, children, and the issue of GBV. It has become evident in numerous families that societal role of mothers has shifted immensely. As a result, many scholars decided to study the various
Fazel Ebrihiam Freeks +2 more
doaj
Childhood Poverty, Early Motherhood and Adult Social Exclusion [PDF]
Childhood poverty and early parenthood are both high on the political agenda. The key new issue addressed in this research is the relative importance of childhood poverty and of early motherhood as correlates of outcomes later in life.
John Hobcraft, Kathleen E Kiernan
core
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
The motherhood penalty in the United Kingdom: An unconditional quantile regression analysis
International Labour ReviewUtilizing data from the UK Household Longitudinal Study, we employ panel methodologies and unconditional quantile regression (UQR) analysis to explore the prevalence and impact of the motherhood penalty within the context of the United Kingdom. Our panel
doaj +2 more sources
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly
Advanced Science, EarlyView.LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang +6 more
wiley +1 more source
Direct and Indirect Effects of Adolescent Motherhood on Under-Five Mortality in Pakistan: Evidence From a Nationally Representative Survey. [PDF]
Am J Hum BiolRabbani N, Zhou Z, Nawaz R, Khalid N.
europepmc +1 more source