Results 141 to 150 of about 64,662 (306)
Advanced Science, EarlyView.In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu +11 more
wiley +1 more source
Advanced Science, EarlyView.In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source
Advanced Science, EarlyView.Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source
Feeding pre-school children : negotiating good motherhood through food [PDF]
Food retains a central importance in family life, which extends beyond its nutritional necessity. Through in-depth interviews with 39 mothers of pre-school children, this study focuses on how mothers negotiate the complex and competing priorities of ...
Bryce, Carol
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Advanced Science, EarlyView.It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou +8 more
wiley +1 more source
Motherhood in breast cancer survivors: Challenges and opportunitiesties [PDF]
Caspian Journal of Internal MedicineReproductive-aged breast cancer (BC) survivors have different ideas regarding the experience of motherhood after cancer treatment. Some BC survivors considered motherhood a miracle of God, an unexpected pleasant event, and an incredible opportunity to ...
Marzieh Azizi +5 more
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Motherhood to Motherhoods: Ideologies of the “Feminine”
The eleven essays in this special issue originated from the “Motherhood to mother-hoods: Ideologies of the ‘Feminine’” conference held at Chapman University in Orange, California, on April 28-30, 2023.
Lee, Nam, Osborn, Jan
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Advanced Science, EarlyView.An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan +10 more
wiley +1 more source
Maternal Ambivalences in Kate Chopin's Selected Works
مجلة كلية التربية للبنات, 2019 The question of motherhood seems to haunt the works of Kate Chopin, a nineteenth century American writer. Though a mother-woman herself, Chopin gives a paradoxical portrait of motherhood in her works.
Instructor Nibras Jawad Kadhim
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