Results 111 to 120 of about 926,913 (367)

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

Policy Brief: Detentions and Removals

open access: yes, 2014
Design and editing: Tings Chak and Rupaleem Bhuyan. This is a Policy Report produced for the Migrant Mothers Project.This research is supported through the Social Sciences and Humanities Research Council’s Standard Research; CERIS, and the University
Migrant Mothers Project
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Community Forum in Kitchener-Waterloo

open access: yes, 2013
Document pulled from the Migrant Mothers Project website in November ...
Migrant Mothers Project
core  

On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy

open access: yesAdvanced Science, EarlyView.
An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley   +1 more source

Policy Brief: Access to Healthcare

open access: yes, 2014
Design and editing: Tings Chak and Rupaleem Bhuyan. This is a Policy Report produced for the Migrant Mothers Project.This research is supported through the Social Sciences and Humanities Research Council’s Standard Research; CERIS, and the University
Migrant Mothers Project
core  

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Policy Brief: Conditional Permanent Residence

open access: yes, 2015
This is a Policy Report produced for the Migrant Mothers Project. This document provides a brief overview of Conditional Permanent Residence impacting sponsored spouses/partners who entered Canada as of October 2012.This research is supported through ...
Migrant Mothers Project
core  

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

open access: yesAdvanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao   +8 more
wiley   +1 more source

Digital Stories: My Personal Story

open access: yes, 2014
"My Personal Story" tells the story of a foreign domestic worker. It follows the hardships of poverty she faced in the Philippines, the exploitation of foreign domestic workers in Hong Kong, and finally, her experience in the Live-In Caregiver Program in
Migrant Mothers Project
core  

Home - About - Disclaimer - Privacy