Results 131 to 140 of about 454,076 (265)

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Digital Stories: Leaving My Child Behind

open access: yes, 2014
Living with precarious status in Canada, "Leaving My Child Behind" examines the ways in which fear and deportation anxiety affects both mother and child as they live "in a constant state of flight or fight." After being denied refugee status, the mother ...
Migrant Mothers Project
core  

Young mothers speak out: Young Pākehā women's experiences of motherhood. [PDF]

open access: yes, 2008
Early motherhood is a much debated and highly contentious topic. This research aimed to explore young Pākehā women's experiences of motherhood using a feminist qualitative framework.
Banks, Hannah
core  

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

open access: yesAdvanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale   +23 more
wiley   +1 more source

The burden of extra uterine growth restriction on postnatal growth in very low birth weight preterm newborns

open access: yesBMC Pediatrics
Background Extra-uterine growth restriction (EUGR) is a condition caused by the failure of very preterm infants to reach their potential growth during the NICU hospital stay. Despite improvements in nutritional supports, their growth pattern is still far
Laura Lucaccioni   +11 more
doaj   +1 more source

Digital Stories: My Eyes have been Opened

open access: yes, 2013
"My Eyes Have Been Opened" is about an immigration story that is fraught with rejection and helplessness. It follows a mother separated from her son as Immigration Officers came knocking at their doors in the middle of the night.
Migrant Mothers Project
core  

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

open access: yesAdvanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu   +12 more
wiley   +1 more source

An exploration of resilience amongst working mothers [PDF]

open access: yes, 2016
M.Phil.Abstract: In this postmodernist study, resilient working mothers are studied by means of an autoethnographical strategy. I accordingly examined a small group of South African working mothers’ experiences, including my own, by blending an evocative
Working mothers   +1 more
core  

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

open access: yesAdvanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang   +5 more
wiley   +1 more source

Digital Stories: Safe Spaces

open access: yes, 2014
"Safe Spaces" offers a story of the experience of working with immigrant women with precarious status living in Canada. It follows a social worker and her journey with her client as their story highlights the important in understanding the difficulties ...
Migrant Mothers Project
core  

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