Results 141 to 150 of about 1,816,378 (344)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Outcomes of neonates with congenital diaphragmatic hernias in South-East Queensland

open access: yesGlobal Pediatrics
Introduction: Congenital diaphragmatic hernias (CDH) affect approximately 1 in 3000 live births (Dingeldein, 2018).1 Neonates with CDH require surgery early in their life to repair the defect in the diaphragm allowing maximal lung expansion without ...
Meghan Jones, Luke Jardine
doaj   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

open access: yesAdvanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge   +21 more
wiley   +1 more source

Self-esteem and mood in obese children and their mothers: A pilot study [PDF]

open access: yes, 2017
Objective: A test-retest pilot study was conducted to examine the relationship between overweight/obesity, self-esteem and mood in a group of school-age children, and the degree to which they changed after a tailored psycho-educational intervention ...
Cassutti, Valentina   +3 more
core  

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Bad Mother / Good Mother

open access: yes, 2020
Bad Mother / Good Mother is an audiovisual performance involving a projection, a modified electronic breast pump as a sound generator, and a sound-reactive LED pumping costume. The project has four songs that critically explore technologies directed specifically at women like breast pumps and fertility extending treatments such as egg-freezing (social ...
openaire   +1 more source

Synchrony, complexity and directiveness in mothers\u27 interactions with infants pre- and post-cochlear implantation [PDF]

open access: yes, 2014
This study investigated effects of profound hearing loss on mother–infant interactions before and after cochlear implantation with a focus on maternal synchrony, complexity, and directiveness.
Bergeson, Tonya R.   +2 more
core   +1 more source

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