Results 31 to 40 of about 926,913 (367)

Postnatal clinical phenotype of five patients with Pallister–Killian Syndrome (tetrasomy 12p): Interest of array CGH for diagnosis and review of the literature

Molecular Genetics & Genomic Medicine, 2019
Background Pallister–Killian syndrome (PKS) is a rare sporadic disorder caused by tetrasomy of the short arm of chromosome 12. The main clinical manifestations are global developmental delay, intellectual disability, epilepsy, dysmorphic features ...
Amerh Salem Alqahtani, Audrey Putoux, Marie Noelle Bonnet Dupeyron, Maryline Carneiro, Laurence Lion‐Francois, Massimiliano Rossi, Hélène Tevissen, Caroline Schluth Bolard, Audrey Labalme, Gaetan Lesca, Marianne Till, Patrick Edery, Damien Sanlaville   +12 more
doaj   +1 more source

Risk factors of breast cancer among patients in a tertiary care hospitals in Afghanistan: a case control study

BMC Cancer, 2021
Background Breast cancer is the second most common causes of women’s death, worldwide. Data on risk factors associated with female breast cancer in the Afghan population is very limited. The aim of our study was to identifying risk factor associated with
Zekrullah Baset, Jamshid Abdul-Ghafar, Yasmin Nadeem Parpio, Ahmed Maseh Haidary   +3 more
doaj   +1 more source

Hemorrhagic ulcerative gastric lymphangioma in an infant: A case report

Journal of Pediatric Surgery Case Reports
Introduction: Lymphangiomas are congenital malformations of the lymphatic system, mostly presenting in the head and neck during early childhood. Its occurrence in the stomach is exceedingly rare with no reported cases in infants to date.
Mohammad Tareq Rahimi, Abdul Wahab Amanat, Haseeb Rahman, Soghra Khaliqi, Nawaz Sharif Kashaf, Roohullah Hares   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Mometasone Furoate–Induced Iatrogenic Cushing’s Syndrome and Secondary Adrenal Insufficiency: A Case Report

Case Reports in Pediatrics
Intranasal corticosteroids (INCS) are widely used to treat allergic rhinitis and nasal obstruction. While their safety profile is generally well established, both local and systemic side effects can occur.
Anna Insalaco, Sara Vandelli, Simona F. Madeo, Patrizia Bruzzi, Viola Trevisani, Barbara Predieri, Laura Lucaccioni, Lorenzo Iughetti   +7 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Complex cytogenetic abnormalities in chronic myeloid leukemia resulting in early progression to blast crisis: a case report

Journal of Medical Case Reports, 2020
Introduction BCR-ABL1, resulting from t(9;22), is the oncogenic driver of chronic myeloid leukemia and the therapeutic target of the disease. Molecular studies have been the gold standard modality for patient assessment since the advent of tyrosine ...
Haider Ali Malakzai, Soma Rahmani, Ahmed Maseh Haidary, Sarah Noor, Maryam Ahmad, Abdul Sami Ibrahimkhil, Samuel Sharif   +6 more
doaj   +1 more source

Giant hamartomatous polyp of the uterine cervix with heterologous mesenchymal tissue in a child: a case report

Journal of Medical Case Reports, 2021
Background Polyps of the uterine cervix are one of the most common benign hyperplastic lesions occurring in the female genital tract that usually arise from the endocervical canal and are believed to be the result of reactive changes due to long-standing
Esmatullah Esmat, Haider Ali Malakzai, Mujtaba Haidari, Ahmed Maseh Haidary, Merwaise Baha, Jamshid Abdul-Ghafar   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Massive inguino-scrotal herniation of urinary bladder in an infant (scrotal cystocele)—case report

Radiology Case Reports, 2020
Scrotal cystocele (massive inguino-scrotal herniation of urinary bladder) is an extremely rare event occurring in pediatric population. Authors present a case of a massive herniation of urinary bladder into the scrotum in a 1-year-old male infant who ...
Naqibullah Foladi, MD, Farhad Farzam, MD, Mohammad Tahir Aien, MD   +2 more
doaj   +1 more source