Results 51 to 60 of about 926,913 (367)

Methylation of the Corticotropin Releasing Hormone Gene Promoter in BeWo Cells: Relationship to Gene Activity

open access: yesInternational Journal of Endocrinology, 2015
Corticotropin releasing hormone (CRH) production by the human placenta increases exponentially as pregnancy advances, and the rate of increase predicts gestational length.
Xin Pan   +6 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Primary hydatid cyst of the neck – EPSC 101593

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Hydatid cyst is a parasitic infection mostly caused by Echinococcus granulosis. The most frequent sites of the cyst are liver and lungs. Occurrence in the head and neck region is extremely rare.
Mohammad Tareq Rahimi   +3 more
doaj   +1 more source

Hypokalemic periodic paralysis in a teenage boy after an intense period of exercise: A rare case report

open access: yesClinical Case Reports, 2023
Key Clinical Messages Diagnosis of rare even can be missed due to less familiarity with the disorder. In patients with muscle weakness, infectious causes are prioritized.
Sahar Noor   +8 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Incidental finding of cardiac hydatid cysts, report of two cases

open access: yesBMC Medical Imaging, 2018
Background Hydatid is a parasitic infection which can affect any organ of body. In some organs like liver and lung; it can be found regularly while in other organs like heart, it is seen very rarely.
Dunya Moghul, Hidayatullah Hamidi
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

When is a ‘Mother’ not a ‘Mother? [PDF]

open access: yesJournal of Social Welfare and Family Law, 2019
No abstract available.
openaire   +1 more source

Metropolitan mothers: Mothers, mothering and paid work [PDF]

open access: yesWomen's Studies International Forum, 2004
This paper reports on the interim findings from a two year ESRC (Economic and Social Research Council) -funded project exploring parental choice of child care for pre school children. The fieldwork is based in two predominantly middle class areas in London.
Vincent, C, Ball, SJ, Pietikainen, S
openaire   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy