Results 71 to 80 of about 1,636,764 (314)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Impact of Intensive Insulin Stabilisation Service in Pregnancy with Type 1 Diabetes

Reproductive Medicine
Background/Objectives: Adverse pregnancy outcomes correlate with blood glucose levels in women with type 1 diabetes (T1DM). There is a gap between the glycaemic targets and the blood glucose control achieved in pregnancy.
Stephanie Teasdale, Natasha Cannon, Alison Griffin, Janelle Nisbet, H. David McIntyre   +4 more
doaj   +1 more source

The Economic Resource Receipt of New Mothers [PDF]

, 2006
U.S. federal policies do not provide a universal social safety net of economic support for women during pregnancy or the immediate postpartum period but assume that employment and/or marriage will protect families from poverty.
Angrist, J., Becker, G. S., Bumpass, L., Chandler, T. D., Cheryl Elman, Coontz, S., Durkheim, E., Edin, K., England, P., Federman, M., Goldin, C., Gordon, L., Hatchett, S. J., Hays, S., Iams, H. M., Kathryn M. Feltey, Laabs, J., Laura Nichols, Martinson, B. C., Mincer, J., Modell, J., Moynihan, D., Murray, C., National Partnership for Women and Families, Patterson, O., Petersen, T., Piven, F. F., Retsinas, N. P., Rossi, A. S., Smith, K. E., Spalter-Roth, R., Stack, C. B., Sweet, J., Sweet, J. A., U. S. Census Bureau, U. S. Census Bureau, U. S. Census Bureau, Wellman, B.   +37 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Incidental finding of cardiac hydatid cysts, report of two cases

BMC Medical Imaging, 2018
Background Hydatid is a parasitic infection which can affect any organ of body. In some organs like liver and lung; it can be found regularly while in other organs like heart, it is seen very rarely.
Dunya Moghul, Hidayatullah Hamidi
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Intra-abdominal retroperitoneal fetus in fetu: A case report

Radiology Case Reports
Fetus in fetu (FIF) is a rare abnormality where a vertebrate parasitic fetus develops inside the body of another normally developing fetus. It is distinct from teratomas, tumors composed of cells from multiple germ layers and have malignant potential ...
Sahar Mahroof, MD, Hasina Noori, MD, Mamoonullah Asmati, MD, MS, MRCS, Adil Zaki, MD   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Mothers’ Everyday Realities and Child Placement Experiences (SUMMARY REPORT) [PDF]

, 2003
Placing a child in substitute care is one of the most challenging aspects of child welfare work. In situations of apprehension, child welfare workers may be required to make quick decisions about child placement sometimes with very limited information ...
Freymond, Nancy Colleen
core   +1 more source

The role of attachment anxiety in parent’s attentional processing of their child’s face : an eye tracking study [PDF]

, 2016
Although mother's attention to offspring is deemed important to support their offspring's secure attachment development, little research tested this association.
Bosmans, Guy, Braet, Caroline, Müller, Sven, van de Brande, Sofie, Vandevivere, Eva   +4 more
core   +2 more sources