Results 151 to 160 of about 88,209 (269)
Developmental Dynamics, EarlyView.Abstract Background Mouse nodal immotile cilia mechanically sense the bending direction for left–right (L–R) determination and activate the left‐side‐specific signaling cascade, leading to increased Nodal activity. Asymmetric distribution of Pkd2, a crucial channel for L–R determination, on immotile cilia has been reported recently. However, the causal
Takanobu A. Katoh +5 more
wiley +1 more source
Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs [PDF]
, 2014 The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure. To create regular, oscilla- tory beating patterns, the activities of the axonemal dyneins must be coordinated both spatially and temporally.
arxiv +1 more source
Reprogrammable Magnetically Actuated Self‐Assembled Cilia Array
Advanced Intelligent Systems, 2023 Motile cilia move in an asymmetric pattern and implement a metachronal wave (MCW) to facilitate fluid movement in a viscous environment. Studies have been conducted to mimic MCW movement of motile cilia, but the fabrication process is too complicating or
Sunwoo Sohn +3 more
doaj +1 more source
Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma
Eye &ENT Research, EarlyView.Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen +3 more
wiley +1 more source
Mixing and transport by ciliary carpets: a numerical study [PDF]
, 2013 We use a 3D computational model to study the fluid transport and mixing due to the beating of an infinite array of cilia. In accord with recent experiments, we observe two distinct regions: a fluid transport region above the cilia and a fluid mixing ...
Ding, Yang +3 more
core +3 more sources
c21orf59/kurly Controls Both Cilia Motility and Polarization [PDF]
Cell Reports, 2016 Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell polarity (PCP). Few factors that regulate both processes have been discovered.
Tse Shuen J Ku +9 more
openaire +3 more sources
Isolated asthenozoospermia: What should we know? A narrative review of literature
UroPrecision, EarlyView.ABSTRACT Male infertility contributes to 20%–70% of infertile couple cases worldwide. One of the key challenges in this area is asthenozoospermia or reduced sperm motility. A particular subset, known as isolated asthenozoospermia (iASZ), in which low motility occurs without abnormalities in sperm count or shape, often goes unnoticed and is not well ...
Ahmed Eissa +7 more
wiley +1 more source
Review of published research on primary dysautonomia of domestic animals
Veterinary Record, EarlyView.Abstract An article published in 1992 by Marion M. Pollin and I.R. Griffiths reviewed the topic of primary dysautonomias of the autonomic nervous system of unidentified origin in multiple domestic species, specifically cats, dogs and horses. Thirty‐one years later, we appear no closer to identifying the causal agents of these strikingly similar ...
Tanith Harte +3 more
wiley +1 more source
Mucociliary Transport in Healthy and Diseased Environments [PDF]
arXiv, 2016 Mucociliary clearance in the lung is the primary defense mechanism that protects the airways from inhaled toxicants and infectious agents. The system consists of a viscoelastic mucus layer driven by motile cilia in a periciliary layer underneath the mucus layer.
arxiv
Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.
, 2015 Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R. +6 more
core +1 more source