Results 171 to 180 of about 88,209 (269)
Andrology, EarlyView.Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas +6 more
wiley +1 more source
Motile and Sensory Cilia Function in Zebrafish
The FASEB Journal, 2015 Advances in developmental genetics and human disease gene cloning have highlighted the essential roles played by cilia in developmental cell fate decisions, left–right asymmetry, and the pathology ...
openaire +2 more sources
Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
Andrology, EarlyView.Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi +5 more
wiley +1 more source
Mutations in Dnaaf1 and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice
G3: Genes, Genomes, Genetics, 2016 We have previously described a forward genetic screen in mice for abnormalities of brain development. Characterization of two hydrocephalus mutants by whole-exome sequencing after whole-genome SNP mapping revealed novel recessive mutations in Dnaaf1 and ...
Seungshin Ha +3 more
doaj +1 more source
Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesis [PDF]
, 2023 Yameng Huang +5 more
openalex +1 more source
DPY-30 Domain and its Flanking Sequence Mediate the Assembly Modulation of Flagellar Radial Spoke Complexes [PDF]
, 2012 RIIa is known as the dimerization and docking (D/D) domain of the cyclic AMP (cAMP)-dependent protein kinase. However, numerous molecules, including radial spoke protein 2 (RSP2) in Chlamydomonas flagella, also contain an RIIa or a similar DPY-30 domain.
Foster, Kenneth W. +2 more
core +1 more source
The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice
Andrology, EarlyView.Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma +7 more
wiley +1 more source
Nonlinear dynamics and fluctuations in biological systems (Habilitation thesis) [PDF]
arXiv, 2018 The present habilitation thesis in theoretical biological physics addresses two central dynamical processes in cells and organisms: (i) active motility and motility control and (ii) self-organized pattern formation. The unifying theme is the nonlinear dynamics of biological function and its robustness in the presence of strong fluctuations, structural ...
arxiv
Cell Proliferation, EarlyView.Our results suggested that mitochondria‐accelerated motile cilia intraflagellar transport may be involved in endometrial microenvironment establishment. ABSTRACT The lack of accurate understanding of cellular physiology and pathophysiology during the WOI constitutes the major obstacle to correct diagnosis and treatment for patients with recurrent ...
Haoxuan Yang +17 more
wiley +1 more source
Effect of curvature and normal forces on motor regulation of cilia [PDF]
arXiv, 2019 Cilia are ubiquitous organelles involves in eukaryotic motility. They are long, slender, and motile protrusions from the cell body. They undergo active regular oscillatory beating patterns that can propel cells, such as the algae Chlamydomonas, through fluids.
arxiv