Results 171 to 180 of about 89,658 (280)

Fluticasone Particles Bind to Motile Respiratory Cilia: A Mechanism for Enhanced Lung and Systemic Exposure? [PDF]

, 2020
Dani Do Hyang Lee, Daniela Cardinale, Wachirun Terakosolphan, Acom Sornsute, Priya Radhakrishnan, Jonathan Coppel, Claire M. Smith, Satyanarayana Somavarapu, Ben Forbes, Christopher O’Callaghan   +9 more
openalex   +1 more source

Prevalence and Nationality Distribution of Known and Novel Genetic Variants in Children With Primary Ciliary Dyskinesia in the State of Qatar

Clinical Genetics, EarlyView.
CT scan image of a 17‐year‐old female with primary ciliary dyskinesia (PCD) showing dextrocardia and bilateral bronchiectasis. The study describes genetic mutations affecting patients with PCD in Qatar and the corresponding clinical phenotype of affected patients.
Atqah AbdulWahab, Reem Mohamed, Amani Hamid, Hadeel Alzoubi, Donald R. Love, Kelly Robinson, Ibrahim Janahi, Mutasim Abu‐Hasan   +7 more
wiley   +1 more source

Failure of centrosome migration causes a loss of motile cilia in talpid³ mutants [PDF]

, 2013
Louise A. Stephen, Gemma M. Davis, Katie E. Mcteir, John James, Lynn McTeir, Martin Kierans, Andrew Bain, Megan G. Davey   +7 more
openalex   +1 more source

Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse

Equine Veterinary Education, EarlyView.
Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx, S. Veraa, J. P. A. M. van Loon, H. Hermans, I. J. M. Slenter, E. M. S. Visser   +5 more
wiley   +1 more source

Core N-DRC components play a crucial role in embryonic development and postnatal organ development

Cell Death and Disease
Motile cilia and flagella are evolutionarily conserved organelles, and their defects cause primary ciliary dyskinesia (PCD), a disorder characterized by systemic organ dysfunction.
Chuan Ren, Shuya Sun, Jiajie Zhu, Shushu Zhou, Xin Zhang, Shuhui Bian, Ying Wang, Jintao Zhang, Mingxi Liu   +8 more
doaj   +1 more source

Assessing the Collective Dynamics of Motile Cilia in Cultures of Human Airway Cells by Multiscale DDM [PDF]

, 2017
Luigi Feriani, Maya Juenet, Cedar Fowler, Nicolas Bruot, Maurizio Chioccioli, Steven M. Holland, Clare Bryant, Pietro Cicuta   +7 more
openalex   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease

, 2020
Wesley Lewis, Erik B. Malarkey, Douglas Tritschler, Raqual Bower, Raymond C. Pasek, Jonathan D. Porath, Susan E. Birket, Sophie Saunier, Corinne Antignac, Michael R. Knowles, Margaret W. Leigh, Maimoona A. Zariwala, Anil K. Challa, Robert A. Keterson, Iaian A. Drummond, John M. Parant, Steven M. Rowe, Friedhelm Hildebrandt, Mary E. Porter, Bradley K. Yoder, Nicolas F. Berbari   +20 more
openalex   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source