Results 201 to 210 of about 88,209 (269)
Advanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer +10 more
wiley +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, Volume 12, Issue 21, June 5, 2025.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin +7 more
wiley +1 more source
Motile cilia hydrodynamics: entrainment versus synchronization when coupling through flow [PDF]
, 2019 Evelyn Hamilton +3 more
openalex +1 more source
Physics of Microswimmers - Single Particle Motion and Collective Behavior
, 2014 Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search for food, orientation toward light, spreading of off-spring, and the formation of colonies are only possible due to locomotion.
Elgeti, Jens +2 more
core +1 more source
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
Cytoskeleton, Volume 82, Issue 6, Page 360-371, June 2025.ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni +9 more
wiley +1 more source
Microfluidic pumping using artificial magnetic cilia
, 2018 One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions.
Alexeev, Alexander +2 more
core +1 more source
Evaluating Adverse Outcomes After Myringotomy or Tube Placement in Head and Neck Cancer
Otolaryngology–Head and Neck Surgery, Volume 172, Issue 6, Page 1971-1979, June 2025.Abstract Objective Evaluate rates of adverse outcomes among patients with a history of head and neck cancer undergoing myringotomy with or without tube placement for middle ear effusion. Study Design Retrospective chart review. Setting Academic medical center.
Krithika Kuppusamy +7 more
wiley +1 more source
Single-particle imaging reveals intraflagellar transport–independent transport and accumulation of EB1 in \u3cem\u3eChlamydomonas\u3c/em\u3e flagella [PDF]
, 2016 The microtubule (MT) plus-end tracking protein EB1 is present at the tips of cilia and flagella; end-binding protein 1 (EB1) remains at the tip during flagellar shortening and in the absence of intraflagellar transport (IFT), the predominant protein ...
Harris, J. Aaron +4 more
core +1 more source
Pediatric Pulmonology, Volume 60, Issue 6, June 2025.ABSTRACT Objective To determine if pediatric patients with laterality defects and meet the diagnostic criteria for primary ciliary dyskinesia (PCD) evaluation are being referred to and evaluated by pediatric pulmonologists. There are organ laterality defects in 50% of patients with PCD.
Alyssa K. Salinas +4 more
wiley +1 more source