Results 211 to 220 of about 88,209 (269)

Protrusion‐Derived Extracellular Vesicles (PD‐EVs) and Their Diverse Origins: Key Players in Cellular Communication, Cancer Progression, and T Cell Modulation

open access: yesBiology of the Cell, Volume 117, Issue 6, June 2025.
Protrusion‐derived extracellular vesicles (PD‐EVs) driving tumor progression and immune modulation. PD‐EVs arise from dynamic cellular extensions and serve as powerful communication tools. In cancer, they reshape the tumor microenvironment, promote angiogenesis and metastasis, and modulate immune responses, including T cell activation.
Mireia Gomez Duro   +4 more
wiley   +1 more source

Spatial Transcriptomics Shows a Distinctive Tumour Microenvironment in the Invasive Versus Premalignant Portion of Early Cutaneous Squamous Cell Carcinoma

open access: yesExperimental Dermatology, Volume 34, Issue 6, June 2025.
In this study, we compared gene expression patterns between the premalignant actinic keratosis (AK) and invasive cutaneous squamous cell carcinoma (SCC) portions within early‐stage cutaneous SCC tissue samples. We identified 29, 14, and 15 differentially expressed genes (DEGs) between the invasive SCC and premalignant AK portions in tumor cells, immune
Jeong‐An Gim   +6 more
wiley   +1 more source

‘Nobody Has Ever Spoken to Me About PCD and Fertility Issues’: Fertility Experiences of People With Primary Ciliary Dyskinesia and Their Family Caregivers

open access: yesHealth Expectations, Volume 28, Issue 3, June 2025.
ABSTRACT Background Primary ciliary dyskinesia (PCD) affects fertility in both females and males. To understand the impact and concerns among people with PCD and parents of affected children (family caregivers), we explored how they report their experiences with fertility.
Leonie D. Schreck   +9 more
wiley   +1 more source

Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia

open access: yesiScience
Summary: Pathogenic variants in KIAA0586/TALPID3 are associated with the ciliopathy Joubert syndrome (JS). We report individuals with KIAA0586/TALPID3 variants affected by primary and motile cilia defects leading to JS and chronic destructive airway ...
Jacqueline E. Taudien   +22 more
doaj  

Discovery of a Vertebrate-Specific Factor that Processes Flagellar Glycolytic Enolase during Motile Ciliogenesis

open access: yesiScience, 2020
Summary: Motile cilia and flagella require ATP for their formation and function. Although glycolytic enzymes are components of flagellar proteomes, how they translocate to flagella is unknown.
Keishi Narita   +4 more
doaj  

Protozoan Co‐Infection Drives Fish Mortality Event in Crete's Karteros River

open access: yesJournal of Fish Diseases, Volume 48, Issue 6, June 2025.
ABSTRACT In August 2024, a significant fish kill involving hundreds of flathead grey mullet (Mugil cephalus) was reported in the delta region of the Karteros River, Crete, Greece. The investigation identified the primary cause of mortality as severe parasitic infections, specifically from the protozoan parasites Amyloodinium ocellatum and Trichodina sp.
Pantelis Katharios   +1 more
wiley   +1 more source

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