Results 71 to 80 of about 957,991 (267)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Beta oscillations predict the envelope sharpness in a rhythmic beat sequence

open access: yesScientific Reports
Periodic sensory inputs entrain oscillatory brain activity, reflecting a neural mechanism that might be fundamental to temporal prediction and perception.
Sabine Leske   +6 more
doaj   +1 more source

Additive opportunistic capture explains group hunting benefits in African wild dogs

open access: yesNature Communications, 2016
African wild dogs hunt collaboratively over long distances in grassland plains. Hubel et al. use high-resolution GPS to show that in their remaining habitat of mixed woodland savannah, African wild dogs use multiple opportunistic short-distance hunts ...
Tatjana Y. Hubel   +5 more
doaj   +1 more source

The semantics of motion

open access: yesProceedings of the seventh conference on European chapter of the Association for Computational Linguistics -, 1995
In this paper we present a semantic study of motion complexes (ie. of a motion verb followed by a spatial preposition). We focus on the spatial and the temporal intrinsic semantic properties of the motion verbs, on the one hand, and of the spatial prepositions, on the other hand.
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Do athletes alter their running mechanics after an Achilles tendon rupture?

open access: yesJournal of Foot and Ankle Research, 2017
Background Over the past thirty years, there has been dramatic increase in incidence of Achilles tendon rupture in the athletic population. The purpose of this study was to compare the lower extremity mechanics of Achilles tendon ruptured runners with ...
Daniel Jandacka   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Motion streaks improve motion detection

open access: yesVision Research, 2007
A number of studies were conducted to determine whether motion-streaks assist motion extraction, and whether a purely motion-based model could account for any observed facilitation. A 3-frame global-motion stimulus was used. Signal dots were manipulated in order to control the strength of the motion-streak.
Edwards, Mark, Crane, Monique
openaire   +3 more sources

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