Results 51 to 60 of about 957,991 (267)

Investigating interbrain synchrony under teamwork disruption: an fNIRS hyperscanning study

Behavioral and Brain Functions
Background Teams are inherently adaptive entities that continuously adapt to changes or disruptions in their tasks or environments. During collaboration, interbrain synchrony (IBS) emerges, reflecting the temporal alignment of neural activity between ...
Coralie Réveillé, Grégoire Vergotte, Gérard Dray, Pierre-Antoine Jean, Pierre Jean, Simon Pla, Stephane Perrey, Grégoire Bosselut   +7 more
doaj   +1 more source

Skiing quality analysis of recreational skiers based on IMU data and self-assessment

Frontiers in Sports and Active Living
Alpine skiing is a popular sport in many countries and holds benefits in terms of health and well-being. At the same time alpine skiing is associated with a certain risk of accidents caused, among other things, by overestimating one’s own skiing skills ...
Christina Kranzinger, Stefan Kranzinger, Eva Hollauf, Harald Rieser, Thomas Stöggl   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A six-week longitudinal dataset of wearable and self-reported stress measurements in working adults

Scientific Data
Stress plays a significant role in energy regulation and mental health. However, the dynamics of long-term stress patterns in daily life and the influence of stress valence on chronic stress and psychological health remain insufficiently understood ...
Christina Halmich, Oliver Jung, Mathias Schmoigl-Tonis, Christoph Schranz, Wolfgang Kremser, Beatrix Kunas, Anton Laireiter   +6 more
doaj   +1 more source

The impact of thigh and shank marker quantity on lower extremity kinematics using a constrained model

BMC Musculoskeletal Disorders, 2018
Background Musculoskeletal models are commonly used to quantify joint motions and loads during human motion. Constraining joint kinematics simplifies these models but the implications of the placement and quantity of markers used during data acquisition ...
Annelise A. Slater, Todd J. Hullfish, Josh R. Baxter   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Super Resolution with Kernel Estimation and Dual Attention Mechanism

Information, 2020
Convolutional Neural Networks (CNN) have led to promising performance in super-resolution (SR). Most SR methods are trained and evaluated on predefined blur kernel datasets (e.g., bicubic).
Huan Liang, Youdong Ding, Fei Wang, Yuzhen Gao, Xiaofeng Qiu   +4 more
doaj   +1 more source