Results 71 to 80 of about 182,415 (256)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Motion capture is motion integration
The phenomenon of “motion capture†has been described as a suppression of the motion of high spatial-frequency (SF) elements in favor of the motion of low SF components, allowing larger forms to capture their smaller features when they move (e.g., Ramachandran, 1990).
Huk, Alexander C., , '96 +2 more
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
3D HUMAN MOTION RETRIEVAL BASED ON HUMAN HIERARCHICAL INDEX STRUCTURE
With the development and wide application of motion capture technology, the captured motion data sets are becoming larger and larger. For this reason, an efficient retrieval method for the motion database is very important.
Qiang Zhang, Xiaocui Guo
doaj
In this paper, we introduce a flexible and inexpensive means for acquiring motion capture data from a human actor or other object. The system described requires just a few pieces of hardware, while leveraging the capabilities of off-the-shelf software to track optical markers in raw film footage.
Staples, Joshua A., Davis, Timothy A.
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Virtual reality (VR) offers built-in wearable sensor-based tracking capabilities. Current research focusses on position and orientation error, with limited results on more clinically relevant metrics, such as joint angles.
Skyler A. Barclay +6 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

