Results 101 to 110 of about 2,340,186 (293)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
TRANSDUCERS FOR MOTION CONTROL
IFAC Proceedings Volumes, 1992 Abstract In order to achieve the levels of functionality that are required in many current engineering systems, information on system status must be provided to the control processor to support the decision making process. In particular, in the majority of systems there will be a need to monitor, either directly or indirectly, a range of motions in ...
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Motion Control via Metric-Aligning Motion Matching
Proceedings of the Special Interest Group on Computer Graphics and Interactive Techniques Conference Conference PapersWe introduce a novel method for controlling a motion sequence using an arbitrary temporal control sequence using temporal alignment. Temporal alignment of motion has gained significant attention owing to its applications in motion control and retargeting.
Naoki Agata, Takeo Igarashi
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Rigid-body motion extracted from total motion of a flexible body [PDF]
, 1967 Control system eliminates or reduces flexibility effects on the manual and automatic control of large flexible vehicles. It extracts rigid-body and flexible-body motion and adapts well when a flexible-body frequency coincides or nearly coincides with the
Howard, J. C.
core +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Stage Motion Control: Nonlinear Integrators Revisited
Annual Review of Control, Robotics, and Autonomous SystemsLinear integrators are well known for their ability to counter static forces and improve low-frequency disturbance rejection properties in control systems. However, linear integrators introduce phase lag, which is a frequency-dependent time shift or delay. Since the early introduction of the Clegg integrator, nonlinear integrators have held the promise
Heertjes, Marcel F. +2 more
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source