Results 91 to 100 of about 10,826,292 (301)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Time-delayed feedback control in astrodynamics [PDF]

, 2009
In this paper we present time-delayed feedback control (TDFC) for the purpose of autonomously driving trajectories of nonlinear systems into periodic orbits.
Biggs, James, BIGGS, JAMES DOUGLAS, McInnes, Colin, Biggs, James D., McInnes, Colin R.   +4 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Mobile Formation Coordination and Tracking Control for Multiple Nonholonomic Vehicles

, 2020
This article addresses forward motion control for trajectory tracking and mobile formation coordination for a group of nonholonomic vehicles on SE(2). First, by constructing an intermediate attitude variable which involves vehicles' position information ...
Peng, Xiuhui, Sun, Zhiyong, Guo, Kexin,, Peng, Xiuhui,, Sun, Zhiyong; id_orcid, Guo, Kexin, Sun, Zhiyong,, Geng, Zhiyong,, Lund University., Geng, Zhiyong   +9 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Differences in Motor Development between Preterm Infants and Full-Term Preschool Children

Children
Although advances in obstetric and neonatal care have improved the survival of preterm infants, many studies document the increased risk of motor and sensory neurodevelopmental abnormalities that can hinder school progress.
Alicia Cuesta-Gómez, Pilar Fernández-González, María Carratalá-Tejada, Inmaculada Aguilar-Bejines   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Ultra-Long, Minor-Diameter, Untethered Growing Continuum Robot via Tip Actuation and Steering

Machines
Continuum robots with outstanding compliance, dexterity, and lean bodies are successfully applied in medicine, aerospace engineering, the nuclear industry, rescue operations, construction, service, and manipulation.
Pan Zhou, Zhaoyi Lin, Lang Zhou, Haili Li, Michael Basin, Jiantao Yao   +5 more
doaj   +1 more source