Results 71 to 80 of about 10,826,292 (301)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Control of a Dynamic Driving Simulator: Time-Variant Motion Cueing Algorithms and Prepositioning [PDF]

open access: yes, 2006
This thesis mainly addresses the task to provide the driver of a dynamic driving simulator with the same motion cues as would occur in reality. The DLR Driving Simulator, which is the subject matter of this thesis, uses a hexapod motion platform to ...
Weiß, Cornelius
core  

Two-Dimensional Motion Perception in Flies [PDF]

open access: yes, 1993
Borst A, Egelhaaf M, Seung HS. Two-Dimensional Motion Perception in Flies. Neural Computation. 1993;5(6):856-868.We study two-dimensional motion perception in flies using a semicircular visual stimulus.
Egelhaaf, M.   +8 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A control system approach to subject specific prospective respiratory motion correction in cardiac MRI [PDF]

open access: yes, 2012
Includes bibliographical references.Respiratory motion of the heart is a problem for high-resolution cardiac MRI. Diaphragmatic navigator gating with a 5mm acceptance window is most commonly used to address this but has an inherently low respiratory ...
Burger, Ian H
core   +1 more source

Preparation and properties of sandwich type density layered porous polyimide materials

open access: yesCailiao gongcheng
Porous polyimide materials (PPI) have interconnected pore structures that can effectively store lubricating oil. However,the presence of these pores will reduce the strength and wear resistance of PPI,resulting in a mutual constraint between its oil ...
YE Zhijian   +7 more
doaj   +1 more source

Motion control: An emergent technology

open access: yesControl Engineering Practice, 1992
Abstract The most relevant aspects in designing a device for the control of a mechanical system are outlined. The peculiarities in the modelling of the load are first indicated. Subsequently, the features of the converter motor unit used for generating the torque are examined.
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Dynamic friction modelling without drift and its application in the simulation of a valve controlled hydraulic cylinder system

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
The frictional modelling literature is reviewed, and it is demonstrated that unrealistic drift results when the shape coefficient is 1.0 for the LuGre and the integral friction models.
Junhong YANG, Andrew PLUMMER, Yong XUE
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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