Results 61 to 70 of about 3,006,826 (294)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

TMA: Temporal Motion Aggregation for Event-based Optical Flow [PDF]

, 2023
Event cameras have the ability to record continuous and detailed trajectories of objects with high temporal resolution, thereby providing intuitive motion cues for optical flow estimation.
Li, Zhijun, Liu, Haotian, Chen, Guang, Knoll, Alois, Jiang, Changjun, Zhang, Yanping, Qu, Sanqing   +6 more
core   +1 more source

Orientation path in Vietnamese: a cognitive-linguistic description

Cogent Arts & Humanities
Over the past few decades, motion in general, and fictive motion in particular, have been central topics in cognitive linguistics. Numerous cognitive linguists have explored these topics across many languages. Their research has provided us with profound
Duong Huu Bien
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Event-based motion correction for PET transmission measurements with a rotating point source

, 2010
Accurate attenuation correction is important for quantitative positron emission tomography (PET) studies. When performing transmission measurements using an external rotating radioactive source, object motion during the transmission scan can distort the ...
Andre Z Kyme, S Meikle (9890720), Meikle, Steven R., Kyme, Andre Z., Fulton, Roger R., Zhou, Victor., Victor W Zhou, A Kyme (9890708), R Fulton (9890711), Steven R Meikle, Roger Fulton, Weidong Zhou (9847925)   +11 more
core   +1 more source

Repetitive motion analysis: segmentation and event classification [PDF]

IEEE Transactions on Pattern Analysis and Machine Intelligence, 2004
Acquisition, analysis, and classification of repetitive human motion for the assessment of postural stress is of central importance to ergonomics practitioners. We present a two-threshold, multidimensional segmentation algorithm to automatically decompose a complex motion into a sequence of simple linear dynamic models.
Chunmei Lu, Nicola J. Ferrier
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On event-based optical flow detection

Frontiers in Neuroscience, 2015
Event-based sensing, i.e. the asynchronous detection of luminance changes, promises low-energy, high dynamic range, and sparse sensing. This stands in contrast to whole image frame-wise acquisition by standard cameras. Here, we systematically investigate
Tobias eBrosch, Stephan eTschechne, Heiko eNeumann   +2 more
doaj   +1 more source