Results 61 to 70 of about 1,398,686 (250)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Inventing entertainment the motion pictures and sound recordings of the Edison companies.
, 1999 Features motion pictures, sound recordings, photographs, and original magazine articles. Includes histories of Edison's invention and manufacture of motion pictures and sound recordings, and a special biography page on Edison, inventor of the phonograph,
Library of Congress. National Digital Library Program. +1 more
core
The Invention of Motion Pictures - from Phenakistoscope to Hollywood.pdf
, 2020 The invention of motion pictures was only possible due to the prior discovery of the phenomenon of persistence of vision, the prior invention of photography and the ability to produce photographs with very brief exposure times.
Rochelle Forrester (692323)
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Fantasy in watching motion pictures. The transportation effect
, 2011 In narrative contexts, transportation has been found to be an important route to persuasion based on realistic stimuli (Green and Brock 2000). After extending transportation to motion pictures trailers, this study shows that (i) individuals high in ...
M. ADDIS +5 more
core
Une goutte d’eau, une goutte d’étoiles. Microcinématographie et avant-garde dans les années 1920
Cinéma & CieA long-standing link exists between avant-garde and scientific cinema. In the 1920s, in fact, the former contributed to the construction of the latter: on the one hand, by its systematic inclusion in film clubs’ and film societies’ screening programs ...
Maria Ida Bernabei
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source