Results 71 to 80 of about 48,874 (313)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Bittoo boss / [PDF]

open access: yes, 2012
Videographer Bittoo is the 'boss' of all weddings in a small-town. In a desperate attempt to make it big, he dabbles in the sex-spy camera business. Will his fate change, or will the good-hearted boy go back to the less-perverted shaadi scene?Pulkit ...
Viacom18 Motion Pictures.   +5 more
core  

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

The Advent of Sound in Motion Pictures [PDF]

open access: yes, 1979
This study traced the developments which led to the advent of sound in motion pictures. The hypothesis that the advent of sound in motion pictures was the result of many technical developments made between 1894 and 1930 was supported by this work ...
McHugh, Michael P.
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Preservation of Digital Motion Pictures in Museums [PDF]

open access: yes, 2019
Thesis (Master's)--University of Washington, 2019Since the turn of the 20th century, motion pictures have been a vital piece of cultural heritage. Over the last 30 years, digital formats have become increasingly popular for the production and storage of
Ford, John D
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Une goutte d’eau, une goutte d’étoiles. Microcinématographie et avant-garde dans les années 1920

open access: yesCinéma & Cie
A long-standing link exists between avant-garde and scientific cinema. In the 1920s, in fact, the former contributed to the construction of the latter: on the one hand, by its systematic inclusion in film clubs’ and film societies’ screening programs ...
Maria Ida Bernabei
doaj   +1 more source

From the Valley to the Hellmouth: “Buffy”’s Transition from Film to Television [PDF]

open access: yesSlayage, 2001
The Buffy who fights demons on television in Sunnydale is a far cry from the Buffy who fought vampires on the big screen in the early nineties. In the transition from film to television, Buffy has mutated from a bubbly Valley girl into a feminist heroine
Gabrielle Moss
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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