Results 61 to 70 of about 7,666,006 (325)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2019 Рассматривается некомпланарный управляемый гелиоцентрический перелёт космического аппарата с неидеально отражающим солнечным парусом к Венере. Целью гелиоцентрического движения является попадание космического аппарата в сферу Хилла Венеры с нулевым ...
Р. М. Хабибуллин
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Waves and instability in a one-dimensional microfluidic array
, 2012 Motion in a one-dimensional (1D) microfluidic array is simulated. Water droplets, dragged by flowing oil, are arranged in a single row, and due to their hydrodynamic interactions spacing between these droplets oscillates with a wave-like motion that is ...
Bin Liu +9 more
core +1 more source
Leida xuebao, 2022 Wide-swath Synthetic Aperture Radar (SAR), represented by TopSAR and ScanSAR acquisition modes, can observe a vast area of ocean scenes. However, achieving wide-swath reduces the quality of imaging resolution, which causes the ships captured in wide ...
Yu LEI +3 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Dynamics Modeling and Hydrodynamic Coefficients Identification of the Wave Glider
Journal of Marine Science and Engineering, 2022 The wave glider is an ocean-wave-propelled autonomous marine vehicle with unique dual-body architecture, which can converse the energy obtained from the ocean wave into the forward thrust.
Xiujun Sun +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Particle motion between parallel walls: Hydrodynamics and simulation [PDF]
, 2010 The low-Reynolds-number motion of a single spherical particle between parallel walls is determined from the exact reflection of the velocity field generated by multipoles of the force density on the particle’s surface.
Brady, John F., Swan, James W.
core