Results 71 to 80 of about 644,825 (278)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A flexible motion tracking system based on inertial sensors

MATEC Web of Conferences, 2018
As a newly emerging human-computer interaction, motion tracking technology offers a way to extract human motion data. This paper presents a series of techniques to improve the flexibility of the motion tracking system based on the inertial measurement ...
Han Zhonghao, Hu Lei, Guo Na, Yang Biao, Liu Hongsheng, Wang Yuhan   +5 more
doaj   +1 more source

Online Motion Agreement Tracking [PDF]

Procedings of the British Machine Vision Conference 2013, 2013
This paper proposes a fast online multi-target tracking method, called motion agreement algorithm, which dynamically selects stable object regions to track. The appearance of each object, here pedestrians, is represented by multiple local patches. For each patch, the algorithm computes a local estimate of the direction of motion.
ZHENG WU, Jianming Zhang, Margrit Betke
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Advanced algorithms for UAV tracking of targets exhibiting start-stop and irregular motion

Scientific Reports
This study presents breakthrough mathematical formulations for UAV tracking that achieve 56.1% HOTA accuracy for targets with start-stop and irregular motion—a 65% improvement over traditional Kalman Filter approaches.
Dinesh Kumar Nishad, Saifullah Khalid, Dharmendra Prakash, Vinay Kumar Singh, Priyanka Sahani   +4 more
doaj   +1 more source

Multi-target Micro-motion Feature Extraction Based on Tracking Pulses in MIMO Radar

Leida xuebao, 2018
The micro-motion feature is one of the important characteristic information of spatial target recognition. However, the existing multifunctional Multi-Input Multi-Output (MIMO) radar usually has to allocate a large number of continuous time resources for
Luo Ying, Gong Yishuai, Chen Yijun, Zhang Qun   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Scaled Brownian motion: a paradoxical process with a time dependent diffusivity for the description of anomalous diffusion

, 2014
Anomalous diffusion is frequently described by scaled Brownian motion (SBM), a Gaussian process with a power-law time dependent diffusion coefficient.
Chechkin, A. V., Jeon, J. -H., Metzler, R.   +2 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source