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A Theoretical and Empirical Analysis of Challenges and motivations of Interdisciplinary Studies Implying on Interdisciplinary Methodology [PDF]

Interdisciplinary Studies in the Humanities, 2011
Purpose, although literature has focused on explaining theoretical background in the area of interdisciplinary studies, a few empirical studies has paid attention to the main reasons of performing interdisciplinary projects.
Mahdi Fatehrad, Mohammad Reza Jalilvand, Monireh Mohammadzade   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Social and Religious Factors in Pilgrimages on the Way of Saint James

Quaestiones Geographicae
This study examines the evolution of the Camino de Santiago into a hybrid of religious pilgrimage and spiritual tourism. Through statistical analysis and interviews with members of the Camino de Santiago Polska Facebook group, the research provides ...
OMELAN ANETA ANNA, FURGAŁA-SELEZNIOW GRAŻYNA, JANKUN-WOŹNICKA MAŁGORZATA   +2 more
doaj   +1 more source

Segmentation of rural tourists: combining push and pull motivations

Tourism and Hospitality Management, 2012
Rural tourism is an important form of tourism in many countries, including Finland. To understand rural tourists’ behaviour and help tourism companies market their products more efficiently many scholars have segmented rural tourists in several different
Juho A. Pesonen
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Promoting socially responsible business at enterprise level: theoretical approach

Journal of Business Economics and Management, 2014
The paper highlights theoretical construct of the new methodological approach presenting the interaction between the corporate social responsibility and the performance of the sustainable enterprise, through the introduction of the methodological ...
Asta Valackienė, Diana Micevičienė
doaj   +1 more source

Who Watches Live Streaming in China? Examining Viewers’ Behaviors, Personality Traits, and Motivations

Frontiers in Psychology, 2020
With millions of viewers globally, live streaming is a new social media that can deliver video content in real time and with many social interaction functions.
Yi Xu, Yixin Ye
doaj   +1 more source

t-Motives

Duke Mathematical Journal, 1986
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources