Results 61 to 70 of about 2,174,411 (342)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Beyond the Planck scale [PDF]

open access: yes, 2009
I outline motivations for believing that important quantum gravity effects lie beyond the Planck scale at both higher energies and longer distances and times.
Giddings, Steven B.
core   +2 more sources

t-Motives

open access: yesDuke Mathematical Journal, 1986
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Characteristics of Patients Seeking and Proceeding with Non-Surgical Facial Aesthetic Procedures

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Sylvia PB Ramirez,1 Gunther Scherz,1 Helen Smith2 1Cutis Medical Laser Clinics Pte Ltd, Singapore; 2Family Medicine and Primary Care, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, SingaporeCorrespondence: Sylvia PB ...
Ramirez SPB, Scherz G, Smith H
doaj  

Promoting socially responsible business at enterprise level: theoretical approach

open access: yesJournal of Business Economics and Management, 2014
The paper highlights theoretical construct of the new methodological approach presenting the interaction between the corporate social responsibility and the performance of the sustainable enterprise, through the introduction of the methodological ...
Asta Valackienė, Diana Micevičienė
doaj   +1 more source

Who Watches Live Streaming in China? Examining Viewers’ Behaviors, Personality Traits, and Motivations

open access: yesFrontiers in Psychology, 2020
With millions of viewers globally, live streaming is a new social media that can deliver video content in real time and with many social interaction functions.
Yi Xu, Yixin Ye
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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