Results 101 to 110 of about 213,335 (302)

Testing the excitability of human motoneurones

Frontiers in Human Neuroscience, 2013
The responsiveness of the human central nervous system can change profoundly with exercise, injury, disuse or disease. Changes occur at both cortical and spinal levels but in most cases excitability of the motoneurone pool must be assessed to localize ...
Chris J Mcneil, Chris J Mcneil, Jane E Butler, Jane E Butler, Janet L Taylor, Janet L Taylor, Simon C. Gandevia, Simon C. Gandevia   +7 more
doaj   +1 more source

Evoked potentials in immobilized cats to a combination of clicks with painful electrocutaneous stimuli [PDF]

Averaged evoked potentials in the auditory, somatosensory, and motor cortical zones, as well as in the mesencephalic reticular formation were recorded in acute experiments on nonanesthetized, immobilized cats.
Gilinskiy, M. A., Korsakov, I. A.
core   +1 more source

Pain-related Somato Sensory Evoked Potentials: A potential new tool to improve the prognostic prediction of coma after cardiac arrest [PDF]

, 2015
INTRODUCTION: Early prediction of a good outcome in comatose patients after cardiac arrest still remains an unsolved problem. The main aim of the present study was to examine the accuracy of middle-latency SSEP triggered by a painful electrical ...
Aric\uf2, Maria, Bendini, Matteo, Bosco, Enrico, Carron, Michele, Linassi, Federico, Mazzarolo, Anna Paola, Ori, Carlo, Scarpa, Bruno, Sorbara, Carlo, Zanatta, Paolo   +9 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The task complexity and Extraversion: an ERP study [PDF]

, 2007
Trying to prove the validity of Eysenck’s theories for the biological basis of personality many data for the differences between extraverts and introverts were collected.
Georgiev, Stiliyan, Lalova, Yordanka, Philipova, Dolja   +2 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Mapping the cortical representation of the lumbar paravertebral muscles [PDF]

, 2007
Objective: The aim of this study was to map the cortical representation of the lumbar spine paravertebral (LP) muscles in healthy subjects. Methods: Transcranial magnetic stimulation (TMS) was employed to map the cortical representations of the LP ...
A.V. Nowicky, Arai, Cariga, D.W. Maskill, Eguchi, Ferbert, Fink, Flor, Gandevia, Godschalk, J. Cossar, Lariviere, Liepert, Maskill, McMillan, N.E. O’Connell, Nowicky, Nudo, Nudo, Nudo, Plassman, Rossini, Schmidlin, Schwenkreis, Sharshar, Sommer, Strutton, Toldi, Tunstill, Wasserman, Wilson, Zanette, Ziemann   +32 more
core   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source