Results 111 to 120 of about 652,652 (273)

KTK MOTOR TEST: REVIEW OF THE MAIN INFLUENCING VARIABLES

open access: yesRevista Paulista de Pediatria
Objective: To analyze the scientific literature regarding the effects of external variables on KTK motor test scores and to verify which motor tests are associated with KTK.
Whendel Mesquita do Nascimento   +2 more
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Efeitos de um programa de jogos pré-desportivos nos aspectos psicobiológicos de idosas

open access: yesRevista Brasileira de Geriatria e Gerontologia
OBJETIVO: Investigar o efeito de um programa de jogos pré-desportivos (JPD) nos aspectos psicobiológicos de idosas. MÉTODOS: 53 voluntárias idosas foram distribuídas em dois grupos: grupo Ativo (n=27) - submetido a um programa de JPD composto por ...
Irene Guarido Luz Bittar   +4 more
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Puckered and JNK signaling in pioneer neurons coordinates the motor activity of the Drosophila embryo. [PDF]

open access: yesNat Commun, 2023
Karkali K   +4 more
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Time estimation during motor activity. [PDF]

open access: yesFront Hum Neurosci, 2023
D'Agostino O   +2 more
europepmc   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

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