Digital HealthObjective This systematic review aims to evaluate current digital twin (DT) applications in healthcare, explore their technological foundations, and propose a roadmap for scalable, patient-centered implementation.
Valeria Calcaterra +7 more
doaj +1 more source
BMC Sports Science, Medicine and Rehabilitation, 2020 Background This study addressed the lack of data on the effect of warm-up (WU) duration in hot-dry climate (~ 30 °C; ~ 18% RH), on thermoregulation, muscular power-output, and fatigue after specific soccer repeated-sprint test (RSA).
Mohamed Frikha +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Selective gating of neuronal activity by intrinsic properties in distinct motor rhythms [PDF]
, 2015 This research has been supported by the Royal Society, Wellcome Trust (089319), and the Biotechnology and Biological Sciences Research Council (BB/L0011X/1). I thank Drs.
Li, Wen-Chang
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Investigation of the interaction between corticomuscular coherence, motor precision and perceived difficulty in wrist flexion and extension [PDF]
, 2013 Includes abstract.Includes bibliographical references.Recently, behavioural (motor precision) differences were reported between isometric wrist flexion and extension.
Divekar, Nikhil Vishwas
core
Identification of inhibitory premotor interneurons activated at a late phase in a motor cycle during Drosophila larval locomotion [PDF]
, 2015 This work was supported by a MEXT/JSPS KAKENHI Grant Numbers, 22115002 (to A.N.) and 221S0003 (to A.N. and Y.I.), and 15H04255 (to A.N.). The work was also supported by Janelia Research Campus (Howard Hughes Medical Institute).Rhythmic motor patterns ...
Nose, Akinao +18 more
core +1 more source
Screen Time, Unhealthy Eating Behaviors, and Associated Health Risks in Children: A Narrative Review
ChildrenIntroduction: The widespread use of digital devices has significantly increased screen time among children and adolescents, raising concerns about its effects on dietary behaviors and health outcomes.
Valeria Calcaterra +12 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
White matter integrity associated with volitional motor activity [PDF]
, 2010 Variations of white matter integrity have been associated with interindividual differences in brain function. Still, little is known about the impact of white matter integrity on quantitative motor behaviour. Diffusion tensor imaging and continuous wrist
Horn, Helge Joachim +6 more
core +1 more source